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To investigate the role of Nir in epidermis during embryogenesis, we crossed mice harboring conditional Nir alleles with the Krt14-Cre deleter strain, which results in Cre-mediated loss of Nir selectively in epidermis. Transciptome analysis of keratinocytes obtained from control and knock-out mice a...
ORGANISM(S): Mus musculus 
2018-03-05 | GSE102277 | GEO
Effects of Rg3@PACVs with NIR in a Rat Model of Pulmonary Ischemia–Reperfusion Injury
To clarify the antibacterial mechanism of AuPt@ZIF-8 + H₂O₂ + NIR, we treated Escherichia coli and Staphylococcus aureus with/without AuPt@ZIF-8 + H₂O₂ + NIR and observed the changes in gene expression using high-throughput transcriptome sequencing.
ORGANISM(S): Escherichia coli Staphylococcus aureus 
2026-06-30 | GSE306179 | GEO
Pulmonary ischemia–reperfusion injury (IRI) is characterized by excessive inflammation, oxidative stress, and mitochondrial dysfunction, leading to severe lung damage. To elucidate the molecular mechanisms underlying the protective effects of a macrophage membrane-coated mesoporous polydopamine nano...
ORGANISM(S): Rattus norvegicus 
2026-03-10 | GSE324247 | GEO
Transcriptomic and metabolomic profiling of Staphylococcus aureus and Escherichia coli treated with AuPt@ZIF-8 + H₂O₂ + NIR or control
Genomics
Transcription Analysis of CZP + NIR treated 4T1 cells
To clarify the effects of near-infrared radiation, we assessed DNA microarray after water-filtered broad-spectrum near-infrared (1100-1800 nm together with a water-filter that excludes wavelengths 1400-1500 nm) irradiation. We performed 5 rounds of near-infrared irradiation (at 10 J ⁄cm2) using 2 ...
ORGANISM(S): Homo sapiens 
Analysis of the RNA-seq data performed in IR vs NIR hematopoietic stem cells show the loss of the TNF_via_NFKB signature. We showed that the loss of this signature could be associated with hematopoietic stem cell gene deregulation. To validate this association, we tested if TNFa treatment before irr...
ORGANISM(S): Mus musculus 
Analysis of the RNA-seq data performed in IR vs NIR hematopoietic stem cells show the loss of the TNF_via_NFKB signature. We showed that the loss of this signature could be associated with H3K9me3 loss at specific retrotransposable elements . To validate this association, we tested if TNFa treatment...
ORGANISM(S): Mus musculus 
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