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MetabolomicsHost NLRP6 exacerbates graft-versus-host disease independent of microbial diversity
Not available
ORGANISM(S): Mus musculus 
ST001089 | MetabolomicsWorkbench
TranscriptomicsGlobal genome expression analysis of lamina propria derived WT and Nlrp6-/- Ly6C-hi inflammatory monocytes
Nlrp6-/- lamina propria Ly6C-hi monocytes in response to AOM/DSS have deficient TNFα production, but increased production of other pro-inflammatory cytokines as compared to WT NLRP6 is a member of the Nod-like receptor family, whose members are involved in the recognition of microbes and/or tissue ...
ORGANISM(S): Mus musculus 
2016-03-27 | E-GEOD-79631 | biostudies-arrayexpress
ProteomicsNLRP6 controls PTEN stability by promoting autophagic degradation of p85α to drive tumorigenesis
To identify NLRP6-associated proteins in living cells, we applied an APEX2-based labelling method combined with mass spectrometry. In brief, APEX2 was genetically fused to NLRP6. In the presence of hydrogen peroxide, APEX2 catalysed biotin-phenol to become a biotin-phenol radical that covalently bou...
ORGANISM(S): Homo sapiens (Human) 
2023-07-02 | PXD037436 | Pride
Nlrp6 Cell 
ProteomicsNLRP6 controls PTEN stability by promoting autophagic degradation of p85α to drive tumorigenesis
To identify NLRP6-associated proteins in living cells, we applied an APEX2-based labelling method combined with mass spectrometry. In brief, APEX2 was genetically fused to NLRP6. In the presence of hydrogen peroxide, APEX2 catalysed biotin-phenol to become a biotin-phenol radical that covalently bou...
ORGANISM(S): Homo sapiens (Human) 
2023-07-02 | PXD037460 | Pride
Human Lc-ms/ms 
GenomicsNLRP6 does not impact mouse microbiota
The NLR protein NLRP6 does not impact gut microbiota composition
PRJEB22561 | ENA
GenomicsNext Generation Sequencing of Wild Type and Nlrp6-/- T cells
Next Generation Sequencing of Wild Type and Nlrp6-/- T cells
PRJNA478531 | ENA
GenomicsNLRP6 in ALD mouse model (A08)
NLRP6 inflammasome modulates disease progression in a chronic-plus-binge mouse model of alcoholic liver disease.
PRJEB48802 | ENA
GenomicsWT and NLRP6 KO CD103+ and CD103- B cell expression
WT and NLRP6 KO CD103+ and CD103- B cell expression
PRJNA931300 | ENA
GenomicsEstrogen Receptor β Activation Inhibits Colitis by Promoting the NLRP6-Mediated Autophagy
Estrogen Receptor β Activation Inhibits Colitis by Promoting the NLRP6-Mediated Autophagy
PRJNA637511 | ENA
TranscriptomicsEstrogen Receptor β Activation Inhibits Colitis by Promoting the NLRP6-Mediated Autophagy
Estrogen receptor β (ERβ) and NOD-, LRR- and pyrin domain-containing 6 (NLRP6) are highly expressed in intestinal tissues and reduce intestinal inflammation, but their underlying mechanisms are unclear. We found that ERβ and NLRP6 levels were reduced in patients with inflammatory bowel disease (IBD)...
ORGANISM(S): Mus musculus 
2023-06-05 | GSE151864 | GEO
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