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Casandra W. Philipson, Josep Bassaganya-Riera, Monica Viladomiu, Barbara Kronsteiner, Vida Abedi, Stefan Hoops, Pawel Michalak, Lin Kang, Stephen E. Girardin & Raquel Hontecillas. Modeling the Regulatory Mechanisms by Which NLRX1 Modulates Innate Immune Responses to Helicobacter pylori Infection. PL...
2024-09-02 | BIOMD0000000596 | BioModels
NLRX1 Limits Inflammatory Neurodegeneration in the Anterior Visual Pathway
Chronic innate immune activation in the central nervous system (CNS) significantly contributes to neurodegeneration in progressive multiple sclerosis (MS). Using multiple EAE models, we explored the potential of the innate immune sensor NLRX1 to protect neurons in the anterior visual pathway from in...
ORGANISM(S): Mus musculus 
2025-01-28 | GSE270482 | GEO
The immune signaling protein NLRX1 can be either tumor promoting or tumor suppressing in different models of cancer. We demonstrate that in a mammary tumor model of triple-negative breast cancer, NLRX1 impacts tumor volume and lung metastasis. We used this microarray to understand what genes and pat...
ORGANISM(S): Mus musculus 
2023-08-01 | GSE216937 | GEO
NLRX1 is a mitochondrial-associated NOD-like receptor that modulates antiviral immunity, cellular stress, autophagy, and reactive oxygen species (ROS) production. The role of NLRX1 in inflammatory bowel disease (IBD) remains largely unknown. This study aimed to characterize NLRX1-mediated mechanisms...
ORGANISM(S): Mus musculus 
2018-03-07 | GSE68419 | GEO
Clariom S Microarray Expression Data from 4T1 parental and transduced tumors collected from WT and Nlrx1-/- mice
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