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TranscriptomicsTranscription profiling of mouse neuromuscular junction laser dissected at various time points vs. normal
NMJ Junction various time points normal C57BL10 LCM mRNA
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-2394 | biostudies-arrayexpress
TranscriptomicsFiber and NMJ / synaptic gene expression comparisons in rat extraocular muscle (EOM) and tibialis anterior (TA) muscle.
Purpose: To examine and characterize the expression profile of genes expressed at the neuromuscular junctions (NMJs) of extraocular muscles (EOMs) in comparison to the NMJs of tibialis anterior muscle (TA). Methods: Adult rat rectus EOMs and TAs were dissected, flash-frozen, serially sectioned and ...
ORGANISM(S): Rattus norvegicus 
2010-04-28 | E-GEOD-15737 | biostudies-arrayexpress
GenomicsThe neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia [NMJ data set].
The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia [NMJ data set].
PRJNA578746 | ENA
TranscriptomicsThe neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia [NMJ data set].
Purpose: To investigate whether our signatures of mTORC1-driven sarcopenia originate from cells residing at the neuromuscular junction (NMJ), we followed laser-capture microdissection with RNA-seq from adult and sarcopenic tibialis anterior (TA) muscles. Methods: TA muscles were incubated in solutio...
ORGANISM(S): Mus musculus 
2020-06-19 | GSE139209 | GEO
UnknownFunctional reconstitution of Drosophila melanogaster NMJ glutamate receptors.
Not available
S-EPMC4434721 | biostudies-literature
TranscriptomicsThe miRNA pathway controls rapid changes in activity-dependent synaptic structure at the Drosophila melanogaster neuromuscular junction (miRNA array)
It is widely accepted that long-term changes in synapse structure and function are mediated by rapid activity-dependent gene transcription and new protein synthesis. A growing amount of evidence suggests that the microRNA (miRNA) pathway plays an important role in coordinating these processes. Despi...
ORGANISM(S): Drosophila melanogaster 
2013-02-01 | E-GEOD-43943 | biostudies-arrayexpress
ProteomicsAxonal TDP-43 Drives NMJ Disruption through Inhibition of Local Protein Synthesis
Mislocalization of the predominantly nuclear RNA/DNA binding protein, TDP-43, occurs in motor neurons of ~95% of ALS patients, but the contribution of axonal TDP-43 to this fatal neurodegenerative disease is unclear. Here, we find TDP-43 accumulation in the axons of intra-muscular nerves from ALS pa...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-04 | PXD021876 | Pride
Lc-ms/ms Mouse Nmj Als Tdp-43 Neurodegeneration 
TranscriptomicsThe miRNA pathway controls rapid changes in activity-dependent synaptic structure at the Drosophila melanogaster neuromuscular junction (RT-PCR)
It is widely accepted that long-term changes in synapse structure and function are mediated by rapid activity-dependent gene transcription and new protein synthesis. A growing amount of evidence suggests that the microRNA (miRNA) pathway plays an important role in coordinating these processes. Despi...
ORGANISM(S): Drosophila melanogaster 
2013-02-01 | E-GEOD-43944 | biostudies-arrayexpress
UnknownNMJ-related diseases beyond the congenital myasthenic syndromes.
Not available
S-EPMC10436495 | biostudies-literature
UnknownNMJ Analyser: a novel method to quantify neuromuscular junction morphology in zebrafish.
Not available
S-EPMC10713120 | biostudies-literature
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