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TranscriptomicsGene expression profiles of spontaneous metastasis in a K-ras/p53 mutant mouse model
The biologic basis for NSCLC metastasis is not well understood. Here we addressed this deficiency by transcriptionally profiling tumors from a genetic mouse model of human lung adenocarcinoma that develops metastatic disease owing to the expression of K-rasG12D and p53R172H. We identified 2,209 gene...
ORGANISM(S): Mus musculus 
2009-04-14 | E-GEOD-14449 | biostudies-arrayexpress
TranscriptomicscDNA microarray analysis of splenic B220+CD138+ plasma cells from K/BxNsf and K/BxN mice
Long-lived plasma cells (LLPCs) develop under the help of follicular helper T (Tfh) cells and reside mainly in the bone marrow. However, these cells are unusually abundant in the spleen of several autoimmune models including K/BxNsf mice, yet their pathogenic impact remains unknown. To investigate a...
ORGANISM(S): Mus musculus 
2016-03-01 | E-GEOD-66947 | biostudies-arrayexpress
MetabolomicsIdentification of BolA protein reveals a novel virulence factor in Klebsiella pneumoniae that contributes to liver abscess in mice

BolA has been characterized as an important transcriptional regulator, which is induced in the stationary phase of growth and is often associated with bacterial virulence. This study was initiated to elucidate the role of the BolA in the virulence of K. pneumoniae. Using a mous...

2022-09-13 | MTBLS2712 | MetaboLights
TranscriptomicsExpression profiling of the forming atrioventricular node using a novel Tbx3-based node-specific transgenic reporter
The atrioventricular (AV) node is a recurrent source of potentially life-threatening arrhythmias. Nevertheless, limited data are available on its developmental control or molecular phenotype. We used a novel AV node-specific reporter mouse to gain insight into the gene programs determining the forma...
ORGANISM(S): Mus musculus 
2009-06-02 | E-GEOD-13614 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse NSCLC metastasis: K-ras/p53 mutant and syngeneic mouse models - super series
This SuperSeries is composed of the following subset Series:; GSE14449: Gene expression profiles of spontaneous metastasis in a K-ras/p53 mutant mouse model; GSE14458: Gene expression profiles of 344SQ lung adenocarcinoma cells with high metastatic potential (syngeneic mouse model) Experiment Overal...
ORGANISM(S): Mus musculus 
2009-11-23 | E-GEOD-14459 | biostudies-arrayexpress
UnknownK-mer Content Changes with Node Degree in Promoter-Enhancer Network of Mouse ES Cells.
Not available
S-EPMC8347099 | biostudies-literature
UnknownTwo-Pore K+ Channel TREK-1 Regulates Sinoatrial Node Membrane Excitability.
Not available
S-EPMC4859279 | biostudies-literature
UnknownRole of the K(Ca)3.1 K+ channel in auricular lymph node CD4+ T-lymphocyte function of the delayed-type hypersensitivity model.
Not available
S-EPMC3696325 | biostudies-literature
TranscriptomicsTranscription profiling of matching human primary head and neck squamous cell carcinomas and cervical lymph node metastases.
An experiment was performed to investigate the perservation of gene expression upon metastasis of primary head and neck squamous cell carcinomas to the cervical lymph node.
ORGANISM(S): Homo sapiens 
2006-10-23 | E-TABM-114 | biostudies-arrayexpress
TranscriptomicsMaize coleoptilar node development: WT vs. rtcs
Maize (Zea mays L.) and other monocot cereals develop extensive shoot-borne root systems from nodal structures of the shoot to secure water and nutrient uptake and provide anchorage in the soil. In the present study, the early stages of coleoptilar node (first shoot-node) development of maize were s...
ORGANISM(S): Zea mays 
2013-09-01 | E-GEOD-25467 | biostudies-arrayexpress
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