This model is from the article:
Temporal Coding of Insulin Action through Multiplexing of the AKT Pathway.
Kubota H, Noguchi R, Toyoshima Y, Ozaki Y, Uda S, Watanabe K, Ogawa W, Kuroda S. Mol Cell.
2012 Jun 29;46(6):820-32. 22633957
, ...
Yugi2014 - Insulin induced signalling (PFKL
phosphorylation) - model 1
Insulin induces phosphorylation and activation of liver-type
phosphofructokinase 1, which thereby controls a key reaction in
glycolysis. This mechanism is revealed using the mathematical
model. In this model, the PFKL ph...
Yugi2014 - Insulin induced signalling (PFKL
phosphorylation) - model 2
Insulin induces phosphorylation and activation of liver-type
phosphofructokinase 1, which thereby controls a key reaction in
glycolysis. This mechanism is revealed using the mathematical
model. In this model, the PFKL ph...
Archival formalin-fixed, paraffin-embedded (FFPE) tissues are invaluable resources for translational research, as clinical outcomes and treatment histories are often available. FFPE blocks provide a standardized and cost-effective alternative to frozen specimens, with formalin-induced protein crossl...
Archival formalin-fixed, paraffin-embedded (FFPE) tissues are invaluable resources for translational research, as clinical outcomes and treatment histories are often available. FFPE blocks provide a standardized and cost-effective alternative to frozen specimens, with formalin-induced protein crossl...
Formalin-fixed paraffin-embedded (FFPE) tissues are crucial clinical archives linked with long-term follow-up data, yet the suitability of deep proteomic analysis on samples stored over 30 years remains largely unexplored. This study aimed to verify the feasibility of deep proteomic analysis on extr...
Tumor and non-tumor tissues from 19 cases of colorectal cancer were examined using DIA-based mass spectrometry. A total of 11,833 proteins were identified, including 531 of the 748 cancer-associated proteins defined in the Catalogue of Somatic Mutations in Cancer. In the comparative analysis between...
FAO cells, rat hepatoma cells, were stimulated with 1 nM insulin and collected at seven time points for ~60 minutes. Ion metal affinity chromatography (IMAC) was performed to enrich the phosphopeptides. As we used two sets of 4-plex iTRAQ to quantify the peptides from seven samples, we set the inter...
