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MetabolomicsDried blood spots analysis for targeted and non-targeted exposomics

Dried blood spots (DBS) are an established sample type, widely used in newborn screening programs for monitoring metabolic diseases. Their minimally invasive nature offers great promise for assessing chemical exposures, particularly during early life stages and in large-scale epidemiological stud...

2025-10-09 | MTBLS13065 | MetaboLights
MetabolomicsNon-targeted metabolomics of mouse feces in response to dietary fiber

Non-targeted metabolomic analysis of fecal samples from mice with and without soy dietary fiber in their diet

2026-03-13 | MTBLS14046 | MetaboLights
MetabolomicsExposomic Biomonitoring of Polyphenols by Non-Targeted Analysis and Suspect Screening

Polyphenols, prevalent in plants and fungi, are investigated intensively in nutritional and clinical settings because of their beneficial bioactive properties. Due to their complexity, analysis with untargeted approaches is favorable, which typically use high-resolution mass spectrometry (HRMS) r...

2025-08-07 | MTBLS7564 | MetaboLights
MetabolomicsBenchmarking non-targeted metabolomics using yeast extract controls

Non-target analysis based on high resolution mass spectrometry calls for quality controls to validate analytical workflows. So far no community-wide used quality control material has been established in metabolomics. In this work, we propose ethanolic yeast extracts derived from Pichia pastoris i...

2020-09-29 | MTBLS1782 | MetaboLights
MetabolomicsCompilation of transcriptomics, non-targeted metabolomics and targeted metabolomics data in bovine mammary epithelial cells stimulated by ten different essential amino acids (Untargeted metabolomics)

Divergence in the non-targeted metabolite profilings of bovine mammary epithelial cells (BMECs) were systematically captured with regard to 10 individual essential amino acid (EAA) availability. BMECs cultured in 6-well plates were first serum-starved overnight and subsequently assigned to 1 of 1...

2024-03-04 | MTBLS7789 | MetaboLights
MetabolomicsNon-targeted metabolomics sequencing of Lactobacillus salivarius fermentation broth
To conduct an in-depth analysis of which metabolites in the antiviral-effective lactic acid bacteria supernatant are playing a role, a pretreatment approach was selected. Non-targeted metabolomic analysis was performed on the differential metabolites between LSD2339-CFS and LSM231-CFS, which exhibit...
2026-06-08 | MTBLS14704 | MetaboLights
MetabolomicsNon-targeted multimodal metabolomics and lipidomics data from ovine rumen fluid fractions

From an animal production and health perspective, our understanding of the metabolites in ruminant biofluids, particularly rumen fluid across different host species is poorly understood. Metabolomics is a powerful and sensitive approach for investigating low molecular weight metabolite profiles p...

2021-08-23 | MTBLS1717 | MetaboLights
MetabolomicsNon-targeted metabolomics analysis of synovial fluid from TMD patients
This study performed non-targeted metabolomics detection on 62 human joint cavity lavage fluid samples using UHPLC-QE-MS. Metabolites were extracted with methanol:acetonitrile (1:1), separated on a Waters ACQUITY UPLC BEH Amide column, and detected by Orbitrap Exploris 120 mass spectrometer in both ...
2026-09-23 | MTBLS14238 | MetaboLights
MetabolomicsMechanisms of action of bile acids in pediatric gastroesophageal reflux: Exploration through non-targeted and targeted metabolomics methods

Purpose: To investigate the pathogenesis of pediatric bile reflux gastritis (BRG) using non-targeted and targeted metabolomics analyses of the changes and content differences of bile acids (BAs) in gastric juice. Methods: Data from 25 pediatric BRG patients treat...

2025-12-05 | MTBLS13459 | MetaboLights
MetabolomicsMechanisms of action of bile acids in pediatric gastroesophageal reflux: Exploration through non-targeted and targeted metabolomics methods

Purpose: To investigate the pathogenesis of pediatric bile reflux gastritis (BRG) using non-targeted and targeted metabolomics analyses of the changes and content differences of bile acids (BAs) in gastric juice. Methods: Data from 25 pediatric BRG patients treated at Jinhua Maternal and Child He...

2025-12-04 | MTBLS13450 | MetaboLights
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