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ProteomicsMorpheus Spectral Counter - Morpheus spectral counter: a computational tool for label-free quantitative mass spectrometry using the morpheus search engine
Label-free quantitative mass spectrometry (MS) based on the Normalized Spectral Abundance Factor (NSAF) has emerged as a simple and reasonably robust method to determine the relative abundance of individual proteins within complex mixtures. Here, we describe Morpheus Spectral Counter (MSpC) as the ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2016-02-24 | PXD003002 | Pride
Proteomics Morpheus Software Bioinformatics Spectral count Label-free quantification Lc-ms/ms 
UnknownMorpheus Spectral Counter: A computational tool for label-free quantitative mass spectrometry using the Morpheus search engine.
Not available
S-EPMC5089804 | biostudies-literature
ProteomicsAnalysis of the interactome of RPS19 mutants
Ribosomal protein S19 (RPS19) is a 16-kDa protein found mainly as a component of the ribosomal 40 S subunit. Its mutations are responsible for Diamond Blackfan anemia, a congenital disease characterized by defective erythroid progenitor maturation. To clarify the function of RPS19, we compare the in...
ORGANISM(S): Homo sapiens (Human) 
2014-08-11 | PXD000640 | Pride
Diamond-blackfan anemia  protein-protein interaction in ribosome 
ProteomicsNew label free methods for protein relative quantification applied to the investigation of animal model of Huntington Disease.
Spectral Counts approaches (SpCs) are largely employed for the comparison of protein expression profiles in label free differential proteomics applications. Similarly, to other comparative methods, also SpCs based approaches require a normalization procedure before Fold Changes (FC) calculation. Her...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-18 | PXD017471 | Pride
Label free methods  spectral counts normalization  complexity-based correction factor  huntington disease mice models 
ProteomicsHost-symbiont proteomes of Bathymodiolus thermophilus
Bathymodiolus mussels inhabiting deep-sea hydrothermal vents harbor bacterial symbionts in their gills, which support the animals’ diet. While the basic mechanisms of energy generation and CO2 fixation that drive these symbioses are largely established, details of molecular interactions between the ...
ORGANISM(S): Bathymodiolus azoricus (Mussel) Bathymodiolus thermophilus 
2019-11-08 | PXD011639 | Pride
Bathymodiolus Symbiosis Hydrothermal vent Symbiont Host Proteome 
ProteomicsProtein-interaction network reveals a role of Prp19 splicing factor in transcription of both intron-containing and intron-less genes
We have previously demonstrated that the transcription-dependent interaction of the promoter and terminator ends of a gene, which results in the formation of a gene loop, is facilitated by the interaction of the general transcription factor TFIIB with the CF1, CPF and Rat1 termination complexes. To ...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2026-02-11 | PXD061187 | Pride
Rnapii Chromatin remodeling Yeast Prp19 splicing factor 
ProteomicsSecretome of Bjerkandera adusta
The secretome of the white-rot fungus Bjerkandera adusta produced in synthetic Kirk medium was compared to that supplemented with an aqueous phenol-rich extract of olive mill residues (ADOR). Distinct changes in the protein composition of oxidoreductases, namely diverse class- II peroxidases and ary...
ORGANISM(S): Bjerkandera adusta 
2018-02-28 | PXD000962 | Pride
Fungi Secretome Lc-ms/ms 
ProteomicsGastric cancer ascites proteome
Gastric cancer is one of the most lethal malignancies with high mortality and gastric cancer-specific biomarker is need due to the lack of specific method for early screening, diagnosis, and prognosis of the patients with gastric cancer. Ascites is known for an important source for conducing biomark...
ORGANISM(S): Homo sapiens (Human) 
2018-04-16 | PXD002213 | Pride
Proteome profiling Proteomics Ascites Gastric cancer Biomarker 
UnknownNew label-free methods for protein relative quantification applied to the investigation of an animal model of Huntington Disease.
Not available
S-EPMC7473538 | biostudies-literature
UnknownSupporting data for comparative proteomic analysis of Listeria monocytogenes ATCC 7644 exposed to a sublethal concentration of nisin.
Not available
S-EPMC4510099 | biostudies-literature
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