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UnknownThe NORMAN Suspect List Exchange (NORMAN-SLE): facilitating European and worldwide collaboration on suspect screening in high resolution mass spectrometry.
Not available
S-EPMC9587084 | biostudies-literature
TranscriptomicsTranscription profiling of mouse kidney treated with with vancomycin to assess nephrotoxicity
The glycopeptide antibiotic vancomycin (VCM) represents one of the last lines of defense against methicillin-resistant Staphylococcus aureus infections. However, vancomycin is nephrotoxic, but the mechanism of toxicity is still unclear. The goal of this study was twofold: (1) gain insights into the ...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7793 | biostudies-arrayexpress
TranscriptomicsResponse of Streptomyces coelicolor to treatment with the antibiotics vancomycin bacitracin and moenomycin A
To determine the response at the transcriptional level of S. coelicolor cells to treatment with 3 antibiotics that target distinct stages of cell wall biosynthesis, biological triplicate cultures of strain M600 were treated with sub-lethal concentrations (10 µg/ml) of vancomycin, bacitracin or moeno...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2011-04-29 | E-MEXP-3032 | biostudies-arrayexpress
TranscriptomicsEffects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: a Randomized Double-blind Placebo-controlled Trial
The gut microbiota has been implicated in obesity and cardiometabolic diseases, although evidence in humans is scarce. We investigated how gut microbiota manipulation by antibiotics (7-day administration of amoxicillin, vancomycin, or placebo) affects host metabolism in 57 obese, prediabetic men. Va...
ORGANISM(S): Homo sapiens 
2016-07-15 | E-GEOD-76003 | biostudies-arrayexpress
TranscriptomicsLong-term growth under elevated CO2 differentially suppresses biotic stress genes in non-acclimated versus cold-acclimated winter wheat
This study compared the photosynthetic performance and the global gene expression of the winter hardy wheat Triticum aestivum cv Norstar grown under non-acclimated (NA) or cold-acclimated (CA) condition at either ambient CO2 or elevated CO2 (EC). CA Norstar maintained comparable light saturated and ...
ORGANISM(S): Triticum aestivum 
2013-08-23 | E-GEOD-48620 | biostudies-arrayexpress
UnknownFirst Report of Bacterial Soft Rot Disease on Pak Choi (Brassica rapa subsp. chinensis) caused by Pectobacterium brasiliense in the United States.
Not available
S-EPMC8446085 | biostudies-literature
TranscriptomicsTranscriptional profiling of the sigma factor sigE deletion mutant of Streptomyces coelicolor (J2130) at 0, 30, 60 and 90 minutes after treatment with sub-lethal concentration of vancomycin.
SigE is a sigma factor found in Streptomyces species and is the key regulator of cell envelope stress response in Streptomyces coelicolor. To determine the regulon of SigE under conditions of cell envelope stress, 10 ug / ml vancomycin was used to induce cell envelope stress in the wild type and a s...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2019-04-24 | E-MTAB-7814 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling of the prostate biopsy samples from African American and European American prostate cancer patients
Prostate cancer (PCa) tends to be more aggressive and lethal in African Americans (AA) compared to European Americans (EA). To further understand the thebiological risk factors associated with PCa disparities observed in AA and EA patients, we performed microRNA profiling using Agilent Human miRNA a...
ORGANISM(S): Homo sapiens 
2015-07-27 | E-GEOD-64318 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of invasive breast cancer events from the tamoxifen prevention trial
Gene expression profiling of invasive breast cancer events from the tamoxifen prevention trial validates low estrogen receptor mRNA level as the main determinant of tamoxifen resistance in estrogen receptor positive breast cancer. In NSABP Breast Cancer Prevention Trial (BCPT), tamoxifen reduced th...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-12665 | biostudies-arrayexpress
TranscriptomicsExpression data in Staphylococcus aureus-infected mice with linezolid and vancomycin treatment
The precise mechanism and effects of antibiotics in host gene expression and immunomodulation in MRSA infection is unknown. Using a well characterized Methicillin Resistant Staphylococcus aureus (MRSA) isolate USA300 in a murine model of infection, we determined that linezolid and vancomycin induced...
ORGANISM(S): Mus musculus 
2014-06-05 | E-GEOD-38531 | biostudies-arrayexpress
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