Novel biomarkers

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Unknown (19847)
Genomics (1984)
Transcriptomics (1324)
Proteomics (817)
Metabolomics (123)
Methylation profiling (89)
Other (60)
Clinical (16)
Genomic (8)
Multiomics (3)
Models (2)

Organisms

Homo sapiens (1667)
Mus musculus (275)
Rattus norvegicus (70)
Bos taurus (20)
Danio rerio (15)
Macaca mulatta (8)
Canis lupus familiaris (8)
Sus scrofa (5)
Eisenia fetida (4)
Equus caballus (4)
Oncorhynchus mykiss (4)
Daphnia magna (4)
Gallus gallus (4)
Salmo salar (3)
Drosophila melanogaster (3)
Taenia multiceps (2)
Pinctada maxima (2)
Mytilus edulis (2)
Campylobacter jejuni (2)
Caenorhabditis elegans (2)
Escherichia coli (2)
Vitis labrusca x Vitis vinifera (1)
Petrolisthes cinctipes (1)
Pimephales promelas (1)
Platichthys flesus (1)
Zea mays (1)
Helicobacter pylori (1)
Echinococcus granulosus (1)
Populus tremula x Populus alba (1)
Glycine max (1)

Organisms

Homo sapiens (903)
Mus musculus (178)
Rattus norvegicus (38)
Bos taurus (9)
Danio rerio (9)
Canis lupus familiaris (7)
human gut metagenome (5)
Macaca mulatta (4)
Ctenopharyngodon idella (3)
Cricetulus griseus (3)
Ovis aries (3)
1,4-dioxane-degrading enrichment culture (2)
Eisenia fetida (2)
Daphnia magna (2)
Gallus gallus (2)
Oncorhynchus mykiss (2)
Sus scrofa (2)
Ophelina (1)
Tradescantia hirsutiflora (1)
Mycobacterium dioxanotrophicus (1)
Pusa hispida hispida (1)
Taenia multiceps (1)
Streptococcus sp. 'group A' (1)
Pinctada maxima (1)
Neogale vison (1)
Fusobacterium nucleatum (1)
Ceratotherium simum simum (1)
Labeo rohita (1)
Camelus bactrianus (1)
Bos (1)

Repository

ENA (1546)
geo (1128)
biostudies-arrayexpress (628)
pride (511)
EGA (174)
iProX (129)
MetaboLights (116)
MassIVE (95)
jPOST (24)
PanoramaPublic (15)
GPMDB (11)
PeptideAtlas (10)
dbGaP (8)
GNPS (7)
PAXDB (3)
BioModels (2)

Tissue

Blood plasma (83)
Cell culture (50)
Blood serum (46)
Brain (32)
Epithelial cell (30)
Cerebrospinal fluid (24)
Liver (24)
Blood (23)
Blood cell (23)
Urine (20)
Lung (17)
Colon (13)
Heart (13)
Kidney (12)
Skin (9)
Plasma Non-glyco (8)
Tear (8)
Lymph node (8)
Saliva (8)
Hepatocyte (6)
Melanocyte (5)
Permanent cell line cell (5)
B cell (5)
Fibroblast (5)
Spleen (5)
Whole body (5)
Bone marrow (4)
Stem cell (4)
Extracellular exosome (3)
Others (2)

Disease

Breast cancer (23)
Alzheimer's disease (19)
Prostate adenocarcinoma (14)
Colon cancer (14)
Not Available (11)
Malignant neoplasm of ovary (11)
Parkinson's disease (11)
Colorectal Neoplasms (7)
Glioblastoma (4)
Rheumatoid arthritis (3)
Normal (2)
Osteosarcoma (2)
Colorectal cancer (2)
Serrated colerectal carcinoma (1)
Early onset preeclampsia (1)
Vitamin B12 deficiency (1)
HIV-associated dementia (1)
Microscopic Polyangiitis (1)
Pre-tumoral lesion in a mouse model of human adamantinomatous craniopharyngioma (ACP) (1)
Renal cancer (1)
Liposarcoma (1)
Small cell lung cancer (1)
None (1)
Colorectal advanced neoplasia (1)
Neoplastic Cells, Circulating (1)
Carcinoma, Hepatocellular (1)
Melanoma (1)
Malignant neoplasm of colon (1)
Colorectal Cancer (1)
Rectal Neoplasms (1)

Technology Type

Mass Spectrometry (511)
Shotgun proteomics (279)
Bottom-up proteomics (93)
Mass spectrometry (87)
SWATH MS (48)
Data-dependent acquisition (43)
Data-independent acquisition (38)
NMR spectroscopy (17)
Mass spectrometry assay (16)
ILLUMINA, Illumina HiSeq 2000 (4)
Illumina HiSeq 2000 (3)
Illumina HiSeq 2000, ILLUMINA (2)
NextSeq 500, Illumina HiSeq 2000, ILLUMINA, Illumina HiSeq 2500 (1)
Illumina OncoArray (1)
ILLUMINA, HiSeq X Ten (1)
ABI_SOLID, Illumina HiSeq 2000, Illumina 450K, AB 5500xl Genetic Analyzer, AB 5500 Genetic Analyzer, ILLUMINA (1)
Illumina HiScanSQ, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina 450K-chip (methylation data) (1)
MeDIP-seq (1)
Infinium_370k - GenomeStudio (1)
Illumina (1)
Illumina Genome Analyzer IIx, Illumina HiSeq 2000 (1)
Illumina HiSeq 2000, Illumina Genome Analyzer IIx (1)
Illumina HiSeq 2500 (1)
Affymetrix SNP 6.0, Illumina HT 12, Aperio image - H&E stained tissue_section (1)
Illumina SNP array, Illumina HiSeq 2000, Agilent CGH array (1)
ILLUMINA, Illumina HiSeq 2000 (ILLUMINA), Illumina HiSeq 2000 (1)
Illumina HiSeq 2000, Illumina Genome Analyzer II, ILLUMINA (1)
Illumina MiSeq (1)

Instrument Platform

Q Exactive (30)
Instrument (11)
Orbitrap Fusion Lumos (11)
NextSeq 500 (8)
LTQ Orbitrap (8)
Illumina NovaSeq 6000 (7)
Q Exactive Plus (7)
Orbitrap Exploris 480 (7)
Illumina HiSeq 2500 (5)
Illumina HiSeq 2000 (5)
Agilent High resolution C scanner (4)
Illumina HiSeq 4000 (4)
Xevo G2-S QTof (3)
Illumina HiScanSQ (2)
Ion Torrent Proton (2)
NextSeq 550 (2)
QTRAP 6500+ (2)
6410 Triple Quadrupole LC/MS (2)
Affymetrix GeneChip Scanner (1)
G2565BA DNA microarray scanner (1)
Illumina protocol (1)
Agilent Bioanalyzer (1)
Not applicable (1)
Agilent 2100 Bioanalyzer (1)
Scanning hardware (1)
Illumina (1)
Illumina HiSeq 1000 (1)
Orbitrap - NEGATIVE (1)
Orbitrap - POSITIVE (1)
Thermo Scientific instrument model|1000494 (1)

Publication Date

2025 (288)
2026 (231)
2022 (197)
2024 (175)
2023 (174)
2021 (154)
2014 (146)
2012 (143)
2020 (137)
2015 (137)
2013 (120)
2010 (107)
2019 (105)
2018 (101)
2016 (97)
2011 (95)
2017 (89)
2008 (42)
2009 (37)
2007 (18)
2006 (6)
2005 (2)
2004 (2)

UNIPROT ID/AC

Q8IIK9_PLAF7 (2)
Q8ILI7_PLAF7 (2)
O96219_PLAF7 (2)
Q8I482_PLAF7 (2)
Q8IAT5_PLAF7 (2)
Q9U0M7_PLAF7 (2)
Q8I5H7_PLAF7 (2)
C0H4N9_PLAF7 (2)
C0H4U0_PLAF7 (2)
Q8IBZ7_PLAF7 (2)
Q8II73_PLAF7 (2)
C6KTF3_PLAF7 (2)
C6KT59_PLAF7 (2)
Q8IL51_PLAF7 (2)
Q8IEN2_PLAF7 (2)
Q8IBP4_PLAF7 (2)
Q8IC14_PLAF7 (2)
C0H5J6_PLAF7 (2)
Q8I3F8_PLAF7 (2)
Q8I5Y1_PLAF7 (2)
Q8I2Q0_PLAF7 (2)
Q8I320_PLAF7 (2)
Q8ILZ3_PLAF7 (2)
A0A143ZZG4_PLAF7 (2)
Q8IJ32_PLAF7 (2)
Q8IIR2_PLAF7 (2)
5833.PF14_0009 (2)
O77361_PLAF7 (2)
5833.PFB0050c (2)
Q8I261_PLAF7 (2)

ENSEMBL ID

ENSG00000170477 (4)
ENSG00000229353 (3)

CHEBI ID

CHEBI:16919 (34)
CHEBI:16737 (33)
CHEBI:30769 (31)
CHEBI:15428 (25)
CHEBI:28044 (24)
CHEBI:17368 (24)
CHEBI:15354 (24)
CHEBI:15756 (23)
CHEBI:27266 (22)
CHEBI:27897 (22)
CHEBI:28300 (21)
CHEBI:25017 (21)
CHEBI:16704 (21)
CHEBI:16449 (20)
CHEBI:18186 (20)
CHEBI:78320 (20)
CHEBI:17754 (20)
CHEBI:17596 (20)
CHEBI:17268 (20)
CHEBI:24898 (19)
CHEBI:27570 (19)
CHEBI:17895 (19)
CHEBI:17750 (19)
CHEBI:15891 (19)
CHEBI:18012 (19)
CHEBI:26986 (18)
CHEBI:16811 (18)
CHEBI:17295 (18)
CHEBI:18237 (18)
CHEBI:16335 (17)

Metabolite Name

Creatinine (22)
Creatine (20)
Choline (18)
Hypoxanthine (18)
L-Phenylalanine (15)
Betaine (14)
Creatinine (13)
Creatine (13)
Valine (13)
L-Carnitine (13)
L-Isoleucine (13)
Taurine (13)
Adenosine (13)
Threonine (12)
Phenylalanine (12)
Glycine (12)
L-Tyrosine (12)
Phenylalanine (12)
Uric acid (12)
L-Proline (12)
Choline (11)
Glucose (11)
Tyrosine (11)
Tryptophan (11)
Isoleucine (11)
Caffeine (11)
Ornithine (11)
Citric acid (11)
Citrate (10)
Valine (10)

First Public Date

2025 (235)
2014 (212)
2026 (202)
2024 (182)
2023 (113)
2021 (102)
2022 (99)
2020 (88)
2019 (75)
2017 (71)
2018 (63)
2015 (56)
2016 (27)
2013 (21)

Modelling Approach

Other (1)
Ordinary differential equation model (1)

Study status

Recruiting (8)
Completed (3)
Not provided (2)
Enrolling by invitation (1)
Active, not recruiting (1)
Not yet recruiting (1)

Lab affiliation

Instituto de Investigaciones Sanitarias de Santiago de Compostela (7)
Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Division of Infection Medicine, Lund, Sweden (5)
Shenzhen People’s Hospital (3)
Proteomics core facility, Biomedical Research Institute, Seoul National University Hospital (3)
Laboratory of Neuroimmunology, Neuroscience Research Centre, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland Service of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland (2)
Protim Irset Inserm U1085 (2)
Unidad de Enfermedad Inflamatoria Intestinal (Servicio de Digestivo). Planta 7 Instituto de Investigación Sanitaria Hospital Universitario de la Princesa. CIBERehd. C/ Diego de León 62. 28006. Madrid. España. (2)
Helmholtz Zentrum München, Institute of Lung Biology and Disease, Group Systems Medicine of Chronic Lung Disease, Member of the German Center for Lung Research (DZL), Munich, Germany (2)
Proteomics Platform cic bioGUNE Bizkaia Tech. Park Build. 800 Derio 48160 Spain (2)
Department of Thoracic Surgery, First Affiliated Hospital of Kunming Medical University, Kunming 650000, Yunnan, China. (2)
Assoc. Prof. at Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark (2)
Metastases Research Laboratory, GIGA-CANCER, University of LIEGE, BELGIUM (2)
Clinical Protein Science & Imaging, Dept. of Measurement Technology and Industrial Electrical Engineering, Lund University, Lund, Sweden (2)
Department of Neurology, Yale School of Medicine, Yale University, new haven CT, USA (2)
Departments of Chemistry and Biochemistry Duke University (2)
1Department of Hematology, Tongji Hospital, Frontier Science Center for Stem Cell Research, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China (2)
Department of Life and Environmental Sciences, University of Cagliari (2)
Nanoparticle Systems Engineering Laboratory Department of Mechanical and Process Engineering ETH Zurich, Switzerland (2)
School of Nursing and School of Medicine, Department of Neurology, Johns Hopkins University, Baltimore, MD, United States (2)
Marcello Manfredi PhD Biological Mass Spectrometry Lab www.biomass-spec.com Department of Translational Medicine (DiMeT) https://www.agingproject.uniupo.it/ Center for Translational Research on Autoimmune & Allergic Diseases - CAAD University of Piemonte Orientale Corso Trieste 15/A, 28100, Novara, Italy Tel. 3334722270 (2)
Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany CECAD, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany (2)
Chang Gung University, Taiwan (2)
Head of Laboratory of Neuro-Oncology, Neurology, Clinical & Cancer Proteomics (2)
Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, 75390, TX, USA (2)
CRUK -CRUK Scotland nstitute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (2)
Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboudumc, Nijmegen, The Netherlands (2)
The University of Sydney (2)
1 Department of Otorhinolaryngology - Head and Neck Surgery, University of Helsinki and HUS Helsinki University Hospital, P.O.Box 263, FI-00029 HUS, Helsinki, Finland 2 Department of Biosciences and Nutrition, Karolinska Institutet, SE-171 76, Stockholm, Sweden. 3 Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland. (2)
OncoProteomics Laboratory, Dept of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands (2)
Medical University of Vienna (2)

Keyword

Irinotecan (2)
Circulating cell free DNA (1)
CRC miRNA (1)
MGMT (1)
Microsatellite stable (1)
First-line (1)
Tolero (1)
Phase 1a / 1b (1)
First in human (1)
Solid Tumors with immunotherapy progression (1)
AXL inhibitor (1)
Advanced Malignancy (1)
EGFR+ NSCLC with progression on ≤2 lines of oral TKIs (1)
BRAF-Mutated CRC (1)
KRAS-Mutated CRC (1)
NRAS-Mutated CRC (1)
Persistent/Recurrent Ovarian Cancer (1)
BRAF-Mutated Melanoma with immunotherapy progression (1)
Colorectal Cancer Peritoneal Metastatic (1)
Tissue sample (1)
Stool sample (1)
NGS (1)
Blood sample (1)
Circulating Tumor Cells (1)
Phase 1 (1)
Temozolomide (1)
Panitumumab (1)
Leucovorin (1)
Bevacizumab (1)
Fluorouracil (1)

IsPrivate

False (2)

Submitter Keywords

Machine Learning Model (1)

Classification

bacteria (5)

Modification

N6 (1)
2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)
57.021464 (1)
4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (410)
RNA-seq of coding RNA (51)
Methylation profiling by array (39)
Comparative genomic hybridization by array (27)
RNA-seq of non coding RNA (24)
Proteomic profiling by array (15)
Other (9)
Observational (9)
Unknown experiment type (8)
Transcription profiling by RT-PCR (8)
Interventional (7)
Genotyping by array (5)
Animal - One-color microarray (4)
Methylation profiling by high throughput sequencing (4)
Cell line - High-throughput sequencing (3)
ChIP-seq (3)
MicroRNA profiling by array (3)
RNA-seq of total RNA (3)
ChIP-chip by SNP array (2)
Human - High-throughput sequencing (2)
ChIP-chip by array (2)
Transcription profiling by SAGE (1)
MeDIP-seq (1)
MicroRNA profiling by high throughput sequencing (1)
Bisulfite-seq (1)
Ribo-seq (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2022 (2685)
2025 (2649)
2021 (2443)
2023 (2296)
2024 (2053)
2020 (1736)
2019 (1217)
2018 (959)
2017 (844)
2016 (738)
2015 (662)
2014 (558)
2013 (365)
2012 (298)
2026 (283)
2011 (226)
2010 (194)
2009 (113)
2008 (83)
2007 (34)
2006 (20)
2005 (9)
2004 (6)
2003 (3)
2002 (1)

Location

Australia (3)
United States (3)
China (2)
Italy (2)
Finland (1)
Saudi Arabia (1)
Israel (1)
South Korea (1)
Germany (1)

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Hyocholic acid species as novel biomarkers for metabolic disorders

Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...

2021-10-06 | MTBLS2343 | MetaboLights

Serum Metabolomics Identifies Novel Prognostic Biomarkers in Amanita Poisoning

Background: Amanita poisoning causes 90-95% of global mushroom-related deaths, yet early prognostic biomarkers for Amanita poisoning are lacking.

Methods: 33 patients with Amanita poisoning were recruited and categorized into survival and death group. Multi...

2025-11-27 | MTBLS13397 | MetaboLights

Multiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

BACKGROUND: Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA). However, the pathogenesis, host-pathogen interaction, and diagnostic markers ...

2022-06-24 | MTBLS3306 | MetaboLights

Novel Potential Diagnostic Serum Biomarkers of Metabolomics in Osteoarticular Tuberculosis Patients: A Preliminary Study

Osteoarticular tuberculosis is one of the extrapulmonary tuberculosis, which is mainly caused by direct infection of Mycobacterium tuberculosis or secondary infection of tuberculosis in other parts. Due to the low specificity of the current detection method, it is leading to a high misdi...

2022-04-08 | MTBLS4187 | MetaboLights

Diagnostic metabolite biomarkers of chronic typhoid carriage

Background: Salmonella Typhi and Salmonella Paratyphi A are the agents of enteric (typhoid) fever; both can establish chronic carriage in the gallbladder. Chronic Salmonella carriers are typically asymptomatic, intermittently shedding bacteria in the feces, and contributing to disease transmission. ...

2018-01-17 | MTBLS579 | MetaboLights

Lipid metabolites as potential diagnostic and prognostic biomarkers for acute community acquired pneumonia

Early diagnosis of acute community-acquired pneumonia (CAP) is important in patient triage and treatment decisions. To identify biomarkers that distinguish patients with CAP from non-CAP controls, we conducted an untargeted global metabolome analysis for plasma samples from142 patients with CAP (CAP...

2016-08-11 | MTBLS354 | MetaboLights

Lipid biomarkers for algal resistance to viral infection in the ocean

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights

Multi-Omics Profiling Reveals Sex-Stratified Biomarkers Predicting Chronicity in Pediatric Primary Immune Thrombocytopenia

Primary immune thrombocytopenia (ITP) is recognized as an acquired autoimmune hemorrhagic disorder distinguished by diminished platelet counts. The efficacy of a sex-stratified multi-omics integrative analytical strategy for forecasting pediatric ITP chronicity was proposed and validated in this ...

2025-09-01 | MTBLS12920 | MetaboLights

Assessment of plasma metabolomic biomarkers in various pediatric diseases

BACKGROUND: Metabolites that are direct read-outs of the functional status of cells, tissues, and organs can be more closely associated with phenotype compared to other omics profiles. Previous studies showed the analytical validity of metabolomic platforms and demonstrated a uti...

2024-05-14 | MTBLS948 | MetaboLights

Metabolic biomarkers of gastric cancer

Plasma samples were analyzed using UPLC-MS/MS untargeted metabolomics. The dataset comprised 144 participants. Partial least squares discriminant analysis (PLS-DA) three-dimensional scores plot distinguishing GC patients from non-GC controls. Metabolic profiling and differential comparison identi...

2026-09-29 | MTBLS12684 | MetaboLights

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