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ProteomicsQuantification of oxidized proteins in wild type and Nox2 deficient mouse dorsal root ganglia
Here we studied the NOX2 dependent redox-proteome in dorsal root ganglia in mice. The overall goal was to assess the degree of NOX2-dependent changes in oxidised proteins following exposure to enriched enviroment and sciatic nerve axotomy in dorsal root ganglia.
ORGANISM(S): Mus musculus (Mouse) 
2020-10-13 | PXD018085 | Pride
Redox proteomics Nox2 Drg 
GenomicsModulation of NOX2 causes Obesity- Mediated Atrial Fibrillation
Modulation of NOX2 causes Obesity- Mediated Atrial Fibrillation
PRJNA1133029 | ENA
GenomicsRole of growth plate Nox2 in alcoholic osteopenia
Role of growth plate Nox2 in alcoholic osteopenia
PRJNA980243 | ENA
GenomicsImpact of NOX2 Deficiency on Microbiota Composition in SPF Mice
NOX2 Deficiency and Microbiota in SPF Mice
PRJEB70607 | ENA
TranscriptomicsModulation of NOX2 causes Obesity- Mediated Atrial Fibrillation
Obesity is linked to an increased risk of atrial fibrillation (AF) via increased oxidative stress. While NADPH oxidase II (NOX2), a major source of oxidative stress and reactive oxygen species (ROS) in the heart predisposes to AF, the underlying mechanisms remain unclear. Here, we studied NOX2-media...
ORGANISM(S): Homo sapiens 
2024-10-09 | GSE271748 | GEO
GenomicsBronchoalveolar lavage alveolar macrophage subset transcriptomes in WT and NOX2-knockout mice
Bronchoalveolar lavage alveolar macrophage subset transcriptomes in WT and NOX2-knockout mice
PRJNA816851 | ENA
TranscriptomicsRole of growth plate Nox2 in alcoholic osteopenia
To study the role of Nox2 in ethanol toxicity on the bone growth plate chondrocytes, we generated Nox2 conditional knockout mice (CKO), in which the catalytic subunit of Nox2, Cybb, is deleted in chondrocytes using a Cre-lox system, where Cre is expressed from the Col2a1 promoter. CKO mice and floxe...
ORGANISM(S): Mus musculus 
2024-05-24 | GSE234176 | GEO
TranscriptomicsBronchoalveolar lavage alveolar macrophage subset transcriptomes in WT and NOX2-knockout mice
The leukocyte NADPH oxidase 2 (NOX2) plays a key role in pathogen killing and immunoregulation. Genetic defects in NOX2 result in chronic granulomatous disease (CGD), associated with microbial infections and inflammatory disorders, often involving the lung. Alveolar macrophages (AM) are the predomin...
ORGANISM(S): Mus musculus 
2022-04-03 | GSE198769 | GEO
TranscriptomicsEffect of NOX2 (CYBB) knock out on the transcriptome of leukemia stem cells isolated from NUP98/HOXA9+BCR/ABL murine syngeneic leukemia model
To investigate the function of NOX2 (CYBB) in leukemia stem cells, we created leukemia by tranforming primitive hematopoetic cells isolated from wild type and NOX2-KO mice with NUP98/HOXA9 and BCR/ABL oncogenes, isolated mRNA, and performed RNA-seq experiments to profile transcriptional changes upon...
ORGANISM(S): Mus musculus 
2019-03-26 | GSE117657 | GEO
UnknownNOX2ko Mice Show Largely Increased Expression of a Mutated NOX2 mRNA Encoding an Inactive NOX2 Protein.
Not available
S-EPMC7692237 | biostudies-literature
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