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Within the family of NADPH oxidases, Nox4 is unique as it is predominantly localized in the endoplasmic reticulum, has constitutive activity and generates H2O2. We hypothesize that these features are consequences of a so far unidentified Nox4-interacting protein. Interacting proteins were screened ...
ORGANISM(S): Homo sapiens (Human) 
2016-02-17 | PXD003514 | Pride
Within the family of NADPH oxidases, Nox4 is unique as it is predominantly localized in the endoplasmic reticulum, has constitutive activity and generates H2O2. We hypothesize that these features are consequences of a so far unidentified Nox4-interacting protein. Interacting proteins were screened ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080772 | MassIVE
Within the family of NADPH oxidases, Nox4 is unique as it is predominantly localized in the endoplasmic reticulum, has constitutive activity and generates H2O2. We hypothesize that these features are consequences of a so far unidentified Nox4-interacting protein. Blue native gel electrophoresis of ...
ORGANISM(S): Homo sapiens (Human) 
2017-04-07 | PXD003509 | Pride
Nox4 effect on mouse articular chondrocytes
Transcriptomic analysis of cardiomyocytes in NOX4 transgenic mice
ORGANISM(S): Mus musculus 
The role of NOX4 in skin fibroblasts
NADPH oxidase 4 (Nox4) deletion accelerates liver regeneration in mice
Exploring the involvement of NOX4 in hypoxia adaptation of papillary thyroid cancer
ABSTRACT Rationale Premature senescence is conducive to aging and cardiovascular diseases. Nrf2 transcription factor, the master orchestrator of adoptive response to cellular stress, has been implicated in regulation of premature senescence in fibroblasts, neural and mesenchymal stem cells by trans...
ORGANISM(S): Homo sapiens (Human) 
2020-08-12 | PXD013640 | Pride
Differentiation of fibroblasts to myofibroblasts is governed by the transforming growth factor beta (TGF-β) through a mechanism involving redox signaling and generation of reactive oxygen species (ROS). Myofibroblasts synthesize proteins of the extracellular matrix and display a contractile phenotyp...
ORGANISM(S): Mus musculus 
2023-03-15 | GSE197562 | GEO
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