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ProteomicsMechanisms Regulating the Function of Spliceosome-Associated Factor Nrl1 of the Fission Yeast Schizosaccharomyces pombe
Pre-mRNA splicing is a key process in the regulation of gene expression as reflected by its disruption in various diseases. Previously, we have demonstrated that the spliceosome-associated factor Nrl1 of the fission yeast S. pombe, except of its role in suppression of accumulation of genome-threaten...
ORGANISM(S): Schizosaccharomyces pombe 927 
2021-07-12 | PXD026669 | Pride
Nrl1  pre-mrna splicing  protein-protein interactions  phosphorylation  cka1  fission yeast 
GenomicsS.pombe nrl1 Study
The spliceosome-associated protein Nrl1 promotes DNA repair and suppresses R-loop formation in fission yeast
PRJEB7937 | ENA
UnknownIdentification of Nrl1 Domains Responsible for Interactions with RNA-Processing Factors and Regulation of Nrl1 Function by Phosphorylation.
Not available
S-EPMC8268110 | biostudies-literature
ProteomicsCoIP of Nrl1 from normal and irradiated fission yeast cells
Nrl1-associated proteins were isolated from wild-type cells untreated or exposed to 100Gy of ionising radiation, and then subjected to LC-MSMS analysis. Identifications were carried out using trypsin as protease.
ORGANISM(S): Schizosaccharomyces pombe 
2016-01-04 | PXD001583 | Pride
Fission yeast Dna repair Splicesosome 
UnknownPlant pathogen effector utilizes host susceptibility factor NRL1 to degrade the immune regulator SWAP70.
Not available
S-EPMC6099861 | biostudies-literature
TranscriptomicsChIP-Chip
The regulation of protein-coding and noncoding RNAs is linked to nuclear processes including chromatin modifications and gene silencing. However, the mechanisms that distinguish RNAs and mediate their functions are poorly understood. We describe a nuclear RNA processing network in fission yeast with...
ORGANISM(S): Schizosaccharomyces pombe 
2013-11-21 | E-MTAB-1962 | biostudies-arrayexpress
UnknownThe spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast.
Not available
S-EPMC4770224 | biostudies-literature
UnknownNRDE-2, the human homolog of fission yeast Nrl1, prevents DNA damage accumulation in human cells.
Not available
S-EPMC6161687 | biostudies-literature
UnknownIdentification of proteins associated with splicing factors Ntr1, Ntr2, Brr2 and Gpl1 in the fission yeast Schizosaccharomyces pombe.
Not available
S-EPMC6619935 | biostudies-literature
UnknownMtr4-like protein coordinates nuclear RNA processing for heterochromatin assembly and for telomere maintenance.
Not available
S-EPMC3974623 | biostudies-literature
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