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ProteomicsDocking a flexible basket onto the core of the nuclear pore complex
The nuclear basket attaches to the nucleoplasmic side of the nuclear pore complex (NPC), coupling transcription to mRNA quality control and export. The basket expands the functional repertoire of a subset of NPCs in S. cerevisiae by drawing a unique RNA/protein interactome. Yet, how the basket docks...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-07-11 | PXD052015 | Pride
Nup153 Nuclear pore complex Mlp2 Nuclear basket Mlp1 Membrane-based reconstitution Y-complex Alphafold screen. Nuclear envelope Slim Nucleocytoplasmic transport Npc assembly Tpr Nup85 Nup60 
GenomicsZC3HC1 has functions distinct from TPR and is dispensable for TPR localization to the nuclear basket
ZC3HC1 has functions distinct from TPR and is dispensable for TPR localization to the nuclear basket
PRJNA1209204 | ENA
ProteomicsNuclear pore complexes interactome dissection
We purified the different types of NPCs in yeast using a differential affinity purification strategy and analyzed their respective compositions and interactomes by mass spectrometry. Therefore, we compared the relative abundancies of specific nuclear factors and NPCs associated factor between all po...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-13 | PXD027872 | Pride
Nuclear pore heterogeneity Affinity purification Mrna maturation 
ProteomicsDistinct Basket Nucleoporins roles in Nuclear Pore Function and Gene Expression
Nuclear pore complexes (NPCs) are important for cellular functions beyond nucleocytoplasmic trafficking, including genome organization and gene expression. This multi-faceted nature and the slow turnover of NPC components complicates investigations of how individual nucleoporins act in these diverse...
ORGANISM(S): Homo sapiens (Human) 
2020-06-30 | PXD020075 | Pride
Auxin-inducible degron Human Nuclear pore complex 
GenomicsTranscriptome analysis of mutations in plant novel nuclear basket protein GBPL3 pnet2_abc mutants
Transcriptome analysis of mutations in plant novel nuclear basket protein GBPL3 pnet2_abc mutants
PRJNA821100 | ENA
TranscriptomicsZC3HC1 has functions distinct from TPR and is dispensable for TPR localization to the nuclear basket
Background: The nuclear basket is a ‘fishtrap’-like structure on the nucleoplasmic face of the nuclear pore complex which has been implicated in diverse functions including RNA export, heterochromatin organisation, and mitosis. Recently, a novel component of the nuclear basket, ZC3HC1, has been desc...
ORGANISM(S): Homo sapiens 
2025-02-18 | GSE286436 | GEO
UnknownThe Molecular Architecture of the Nuclear Basket.
Not available
S-EPMC10996695 | biostudies-literature
UnknownThe molecular architecture of the nuclear basket.
Not available
S-EPMC11416316 | biostudies-literature
UnknownMeiotic nuclear pore complex remodeling provides key insights into nuclear basket organization.
Not available
S-EPMC9754704 | biostudies-literature
ProteomicsMeiotic Nuclear Pore Complex Modularity Provides Key Insights into Nuclear Basket Organization
Using phosphoproteomics and time-lapse fluorescence microscopy, we report that NPCs nuclear pore complexes (NPCs) undergo two distinct modularity events for the nucleoporins Nup60 and Nup2 during budding yeast meiosis: partial and full nuclear basket detachment.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-12-08 | PXD033245 | Pride
Nup2 Dia Time-lapse fluorescence microscopy Swath Phosphoproteomics Saccharomyces cerevisiae Nup60 
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