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Reduced estrogen action is associated with obesity and insulin resistance. However, the cell and tissue-specific actions of estradiol in maintaining metabolic health remain inadequately understood, especially in men. We observed that skeletal muscle ESR1/Esr1 (encodes estrogen receptor α) is posi...

2025-04-09 | MTBLS914 | MetaboLights
Mycoplasma gallisepticum belongs to the class Mollicutes. It causes chronic respiratory disease in avian species. M. gallisepticum is characterized by lack of cell wall; reduced genome size and the volume of its nucleoid is comparable to the size of the whole cell. As a result of genome reduction, M...
ORGANISM(S): Mycoplasma gallisepticum S6 
2021-03-31 | PXD025107 | Pride
Plastids contain multiple copies of the plastid chromosome, folded together with proteins and RNA into nucleoids. The degree to which components of the plastid gene expression and protein biogenesis machineries are nucleoid associated, and the factors involved in plastid DNA organization, repair, an...
ORGANISM(S): Zea mays (Maize) 
2023-09-28 | PXD045331 | Pride
Mycoplasma gallisepticum (MG) is one of the smallest free-living and self-replicating organisms, it is characterized by lack of cell wall and reduced genome size. As a result of genome reduction, MG has a limited variety of DNA-binding proteins (DBP) and transcription factors. To investigate the dyn...
ORGANISM(S): Mycoplasma gallisepticum S6 
2020-05-12 | PXD019077 | Pride
The principal virulence determinant of Mycobacterium tuberculosis (Mtb), the ESX-1 protein secretion system, is positively controlled at the transcriptional level by EspR. Depletion of EspR reportedly affects a small number of genes, both positively or negatively, including a key ESX-1 component, th...
ORGANISM(S): Mycobacterium tuberculosis 
Supporting TMT MS data for paper (doi: 10.1016/j.neuron.2021.12.029) by Goldsmith J. et al., titled "Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons". Index of RAW files uploaded: AO3068-3079: Fractionated (12 fr...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-08-01 | MSV000092565 | MassIVE
In this project, we aimed at identifying H-NS proteins co-purified with two nucleoid-associated proteins (NAPs) in Burkholderia cenocepacia H111 under standard growth conditions. We created strains expressing FLAG-tagged NAPs in addition to the untagged proteins, carried out co-immunoprecipitation e...
ORGANISM(S): Burkholderia cenocepacia H111 Bacteria 
2026-07-21 | PXD070299 | Pride
Nucleoid-associated proteins (NAPs) are small, highly abundant regulators with low sequence specificity and pleiotropic mutant phenotypes. They are involved in transcriptional and post-transcriptional control of gene expression, DNA protection/repair and nucleoid structuring. Discovery of the major ...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2013-04-24 | PRD000736 | Pride
Condensation of nucleoid during environmental adaptation is regulated by dynamic HU interactions
Chloroplast nucleoid is organized by membrane association of transcribed genes [ATAC]
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