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GenomicsVirulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein
The principal virulence determinant of Mycobacterium tuberculosis (Mtb), the ESX-1 protein secretion system, is positively controlled at the transcriptional level by EspR. Depletion of EspR reportedly affects a small number of genes, both positively or negatively, including a key ESX-1 component, th...
ORGANISM(S): Mycobacterium tuberculosis 
2012-04-02 | E-GEOD-35149 | biostudies-arrayexpress
ProteomicsProteomic profile of nucleoid-associated proteins isolated from Mycoplasma gallisepticum in different growth phases
Mycoplasma gallisepticum (MG) is one of the smallest free-living and self-replicating organisms, it is characterized by lack of cell wall and reduced genome size. As a result of genome reduction, MG has a limited variety of DNA-binding proteins (DBP) and transcription factors. To investigate the dyn...
ORGANISM(S): Mycoplasma gallisepticum S6 
2020-05-12 | PXD019077 | Pride
Mycoplasma gallisepticum Synchronous growth Dia Nucleoid Nucleoid associated proteins 
ProteomicsData on nucleoid-associated proteins isolated from Mycoplasma gallisepticum after intracellular infection
Mycoplasma gallisepticum belongs to the class Mollicutes. It causes chronic respiratory disease in avian species. M. gallisepticum is characterized by lack of cell wall; reduced genome size and the volume of its nucleoid is comparable to the size of the whole cell. As a result of genome reduction, M...
ORGANISM(S): Mycoplasma gallisepticum S6 
2021-03-31 | PXD025107 | Pride
Mycoplasma gallisepticum Shotgun proteomics Intracellular infection Lc-ms/ms Nucleoid-associated peoteins 
TranscriptomicsThe nucleoid-associated protein HU controls three regulons that coordinate virulence and general physiology in Salmonella enterica serovar Typhimurium
The regulon of genes controlled by the HU nucleoid-associated proteins was examined in Salmonella enterica serovar Typhimurium (S. Typhimurium). DNA microarrays were used to detect the effect on the bacterial transcriptome of knockout mutations in the hupA, the hupB and in both the hupA and hupB gen...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2011-03-22 | E-GEOD-22860 | biostudies-arrayexpress
GenomicsSMC translocation is unaffected by an excess of nucleoid associated proteins in vivo
SMC translocation is unaffected by an excess of nucleoid associated proteins in vivo
PRJNA1123659 | ENA
GenomicsMultiscale structuring of the E. coli chromosome by nucleoid-associated and condensin proteins
Multiscale structuring of the E. coli chromosome by nucleoid-associated and condensin proteins
PRJNA421326 | ENA
TranscriptomicsChIP-chip of HA-tagged Lsr2 in Mycobacterium tuberculosis and Mycobacterium smegmatis
Bacterial nucleoid-associated proteins play important roles in chromosome organization and global gene regulation. We find that Lsr2 of Mycobacterium tuberculosis is a novel nucleoid-associated protein that specifically binds AT-rich regions of the genome, including regions encoding major virulence ...
ORGANISM(S): Mycobacterium smegmatis 
2010-06-19 | E-GEOD-18652 | biostudies-arrayexpress
ProteomicsNucleoid-Enriched Proteomes in Developing Plastids and Chloroplasts from Maize Leaves: A New Conceptual Framework for Nucleoid Functions
Plastids contain multiple copies of the plastid chromosome, folded together with proteins and RNA into nucleoids. The degree to which components of the plastid gene expression and protein biogenesis machineries are nucleoid associated, and the factors involved in plastid DNA organization, repair, an...
ORGANISM(S): Zea mays (Maize) 
2023-09-28 | PXD045331 | Pride
Proplastids Nucleoids Maize Leaf development Chloroplasts 
UnknownIdentification of nucleoid associated proteins (NAPs) under oxidative stress in Staphylococcus aureus.
Not available
S-EPMC5625760 | biostudies-literature
UnknownEscherichia coli CrfC Protein, a Nucleoid Partition Factor, Localizes to Nucleoid Poles via the Activities of Specific Nucleoid-Associated Proteins.
Not available
S-EPMC6374313 | biostudies-literature
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