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Regulation of chromatin dynamics by a calcium-dependent nucleoskeleton
Growth factors selectively activate calcium signaling pathways in the cell nucleus, which in turn regulate gene transcription and other intra-nuclear events, but the specific way this is accomplished is not entirely understood. The present study shows that growth factors increase inositol 1,4,5-tris...
ORGANISM(S): Homo sapiens 
2026-05-11 | GSE324124 | GEO
The nuclear basket (NB) is an essential structure of the nuclear pore complex (NPC). It serves as a dynamic and multi-functional platform that participates in various critical nuclear processes, including cargo transport, molecular docking, and gene expression regulation. However, the compositional ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-08-25 | PXD032906 | Pride
Nucleoskeleton is generally considered to be the grid structure involved in regulation of genome expression and maintenance in the eukaryotic nucleus. However, its actual biological functions and mechanisms remain controversial. Here, we show the nuclear mitotic apparatus protein (NuMA), an essentia...
ORGANISM(S): Homo sapiens 
2024-03-01 | GSE227707 | GEO
Nucleoskeleton is generally considered to be the grid structure involved in regulation of genome expression and maintenance in the eukaryotic nucleus. However, its actual biological functions and mechanisms remain controversial. Here, we show the nuclear mitotic apparatus protein (NuMA), an essentia...
ORGANISM(S): Homo sapiens 
2024-03-01 | GSE227705 | GEO
Nucleoskeleton is generally considered to be the grid structure involved in regulation of genome expression and maintenance in the eukaryotic nucleus. However, its actual biological functions and mechanisms remain controversial. Here, we show the nuclear mitotic apparatus protein (NuMA), an essentia...
ORGANISM(S): Homo sapiens 
2024-03-01 | GSE227940 | GEO
Nucleoskeleton is generally considered to be the grid structure involved in regulation of genome expression and maintenance in the eukaryotic nucleus. However, its actual biological functions and mechanisms remain controversial. Here, we show the nuclear mitotic apparatus protein (NuMA), an essentia...
ORGANISM(S): Homo sapiens 
2024-03-01 | GSE227704 | GEO
The nucleoskeleton protein NuMA maintains local chromatin architecture partially through promoting linker histone H1’ binding to chromatin and nucleosome stacking [RNA-Seq]
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