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In this work the genomic expression of two Burkholderia cenocepacia clonal variants (IST439 and IST4113) were compared. These isolates were collected from a chronically colonized cystic-fibrosis patient that has died from the cepacia syndrome. IST439 was the first B. cenocepacia isolate recovered f...
ORGANISM(S): Burkholderia cenocepacia 
Our goal was to determine if histone H1 is involved in transcription regulation. RNA interference was used to deplete histone H1 from bloodstream form T. brucei in culture. Total RNA was extracted and RNAseq was used to compare the expression profile of H1 depleted clones and parental cell-line.
ORGANISM(S): Trypanosoma brucei brucei 
Identification of miRNAs in the xylem of Eucalyptus globublus. Samples were taken from different seasons and at different time points from the tension and opposition wood of bent branches.
ORGANISM(S): Eucalyptus globulus 
We performed a microarray analysis to compare the expression profile of azurin treated and untreated with different P-cadherin expression levels. We also compared the differentially expressed genes regulated by P-cadherin overexpression. Both cell lines presented an up-regulation of apoptosis mediat...
ORGANISM(S): Homo sapiens 
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by a marked decline in cognition and memory formation. Increasing evidence highlights the essential role of neuroinflammatory and immune-related molecules, namely the ones that are produced at the brain barriers, on brain immune...
ORGANISM(S): Mus musculus 
Major depression is a multidimensional disorder highly prevalent in modern society. Although several classes of antidepressants (ADs) are currently available to treat depression, the effectiveness of treatment is still limited, as many patients do not show full remission; thus, there is a need to fi...
ORGANISM(S): Rattus norvegicus 
Lymphotoxin-mediated activation of the lymphotoxin-β receptor (LTβR) has been implicated in several physiological and pathological processes, including lymphoid organ development, T-cell maturation, and solid and hematopoietic malignancies. Its role in T-cell acute lymphoblastic leukemia (T-ALL) o...
ORGANISM(S): Homo sapiens 
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