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GenomicsQuantitative Analysis of Erythroblast Transcriptomes in Control and NUP-17d Treatment Groups
Quantitative Analysis of Erythroblast Transcriptomes in Control and NUP-17d Treatment Groups
PRJNA736071 | ENA
TranscriptomicsChromosome-wide mapping of interactions of yeast nucleoporin Nup2 on chromosome VI.
This series is a complementary data set for the manuscript entitled "Nup-PI: The Nucleopore-Promoter Interactions of Genes in Yeast." (Mol. Cell, 2006). Experimental Background: Genomic interaction sites of nuclear proteins were mapped by the in vivo ChEC technique described in Schmid et al. (2004)...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-05 | E-GEOD-3756 | biostudies-arrayexpress
ProteomicsEffect of truncation mutants of the trypanosomatid nuclear lamina protein NUP-1 on the whole cell proteome in T. brucei
The nuclear lamina has multiple functions, including maintaining nuclear structural integrity and differential gene expression. Correct spatial and temporal lamina assembly is essential to meet these and other roles. Recently, it emerged that multiple lamina systems exist that are likely products of...
ORGANISM(S): Trypanosoma brucei brucei TREU927 
2021-06-03 | PXD019978 | Pride
Lamina Trypanosoma Nuclear organisation Molecular assembly Heterochromatin 
TranscriptomicsT. Brucei, Nup-1 Depletion
Organization of the genome into compacted chromatin is a eukaryotic innovation facilitating increased sophistication in transcriptional regulation. In metazoa coiled-coil lamin proteins are major components of the chromatin organizer at the nuclear periphery and maintain nuclear integrity. While ide...
ORGANISM(S): Trypanosoma brucei 
2011-12-15 | E-GEOD-26256 | biostudies-arrayexpress
TranscriptomicsT. Brucei, Nup-1 Depletion
Organization of the genome into compacted chromatin is a eukaryotic innovation facilitating increased sophistication in transcriptional regulation. In metazoa coiled-coil lamin proteins are major components of the chromatin organizer at the nuclear periphery and maintain nuclear integrity. While ide...
ORGANISM(S): Trypanosoma brucei 
2011-12-15 | GSE26256 | GEO
TranscriptomicsQuantitative Analysis of Erythroblast Transcriptomes in Control and NUP-17d Treatment Groups
NUP-17d (17d) is an effective inhibitor of Plek2 protein. NUP-17d treatment inhibits erythroblast proliferation, differentiation and enucleation in a dose-dependent manner via directly binding to Plek2 protein. To reveal the detailed involving mechanism of NUP-17d treatment, we performed RNA sequenc...
ORGANISM(S): Mus musculus 
2021-06-09 | GSE176397 | GEO
UnknownNUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions.
Not available
S-EPMC3313915 | biostudies-literature
GenomicsGenome-wide mapping of MLL1, CRM1, and NUP-fusion derivatives in human leukemia or mouse ES cell lines
Genome-wide mapping of MLL1, CRM1, and NUP-fusion derivatives in human leukemia or mouse ES cell lines
PRJNA837475 | ENA
GenomicsGenome-wide mapping of MLL1, CRM1, and NUP-fusion derivatives in human leukemia or mouse ES cell lines
We used ChIP-seq to examine the genome-wide binding of MLL1, CRM1, and NUP-fusions in human leukemia or mouse ES cell lines. Our analysis revealed that MLL1, CRM1, and NUP-fusions are preferentially co-localized on the genome.
ORGANISM(S): Mus musculus Homo sapiens 
2023-07-27 | GSE202837 | GEO
Genomics
RNA-seq for NUP-1 deletion mutants
PRJNA642306 | ENA
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