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ProteomicsProteomic and bioinformatic characterization of extracellular vesicles released from human primary macrophages upon influenza A infection
We have previously shown that IAV infection of human monocyte-derived macrophages causes major alterations to subcellular protein trafficking inside the cell and triggers robust protein secretion (Lietzén et al, 2011). Here, we have used high-throughput proteomics to identify proteins secreted in ex...
ORGANISM(S): Homo sapiens (Human) 
2017-02-07 | PXD004424 | Pride
Lc-msms Extracellular vesicle Human primary macrophages Influenza a 
ProteomicsProteomic and bioinformatic characterization of extracellular vesicles released from human primary macrophages upon influenza A infection
We have previously shown that IAV infection of human monocyte-derived macrophages causes major alterations to subcellular protein trafficking inside the cell and triggers robust protein secretion (Lietzén et al, 2011). Here, we have used high-throughput proteomics to identify proteins secreted in ex...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-16 | MSV000080643 | MassIVE
Proteomics: Seminal Extracellular Vesicles – A New Frontier in Biomarker Discovery Through Protocol Optimization
: Seminal extracellular vesicles (EVs) hold a promise as a source of biomarkers for urogenital diseases. Unlocking their potential in clinical research requires further investigation to optimize the isolation protocols of these vesicles from semen. This study compares different isolation techniques ...
ORGANISM(S): Homo sapiens (Human) 
2026-10-26 | PXD069636 | Pride
Exosomes Extracellular vesicles Ev isolation : seminal fluid Ev-based biomarkers 
MetabolomicsGNPS - Ancestral allele of DNA polymerase gamma modifies antiviral tolerance
Mitochondria are arising as critical modulators of antiviral tolerance by releasing mtDNA/mtRNA fragments to cytoplasm upon infection, activating virus sensors and type-I interferon response. The relevance of these mechanisms for mitochondrial diseases remains understudied. Here, we investigated mit...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-12-11 | MSV000093634 | GNPS
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