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UnknownStrong Plasmon-Exciton Coupling in Ag Nanoparticle-Conjugated Polymer Core-Shell Hybrid Nanostructures.
Not available
S-EPMC7570213 | biostudies-literature
GenomicsWhole genome DNA methylation of undifferentiated spermatogonia of postnatal day 14 (P14) wild-type and Spocd1-K464A (does not interact with TPR) homozygous mutant mice
In the male mouse germline, PIWI-interacting RNAs (piRNAs), bound by the PIWI protein MIWI2 (PIWIL4), guide the DNA methylation of young active transposable elements (TEs) through SPOCD1. We find that SPOCD1 interacts with the nuclear pore protein TPR, and that this interaction is required to preven...
ORGANISM(S): Mus musculus 
2025-11-12 | E-MTAB-14862 | biostudies-arrayexpress
TranscriptomicsBiochemical Identification of Targets of Individual MicroRNAs in Mouse Embryonic Stem Cells
Mouse Embryonic Stem (ES) cells express a unique set of microRNAs (miRNAs), the miR-290-295 cluster. To elucidate the role of these miRNAs and how they integrate into the ES cell regulatory network requires identification of their direct regulatory targets. The difficulty, however, arises from the l...
ORGANISM(S): Mus musculus 
2010-02-27 | E-GEOD-20199 | biostudies-arrayexpress
ProteomicsTEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing.
The PIWI protein MIWI2 and its associated PIWI-interacting RNAs (piRNAs) instruct DNA methylation of young active transposable elements (TEs) in the male germline. Here we show that MIWI2 associates with TEX15 in foetal gonocytes. TEX15 is predominantly a nuclear protein that is not required for piR...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-18 | PXD019087 | Pride
Mouse transposon silencing 
ProteomicsA nowhere-to-hide mechanism ensures complete piRNA-directed LINE1 methylation
The mouse PIWI-interacting RNA (piRNA) pathway provides anti-transposon immunity to the developing male germline by directing transposon DNA methylation. The first step in this process is the recruitment of SPOCD1 to young LINE1 loci 1 followed in the second step by piRNA-mediated tethering of the P...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-11 | PXD060851 | Pride
Piwi proteins Pirna Spocd1 and tpr Germline Transposons 
Unknown'What if I'm not dead?' - Myth-busting and organ donation.
Not available
S-EPMC6587533 | biostudies-literature
UnknownAdvanced airway assessment techniques.
Not available
S-EPMC8377241 | biostudies-literature
UnknownThe impact of hypothetical PErsonalised Risk Information on informed choice and intention to undergo Colorectal Cancer screening colonoscopy in Scotland (PERICCS)-a randomised controlled trial.
Not available
S-EPMC7574531 | biostudies-literature
UnknownInvestigating the Effects of Threatening Language, Message Framing, and Reactance in Opt-Out Organ Donation Campaigns.
Not available
S-EPMC8691393 | biostudies-literature
Unknown'It's like being conscripted, one volunteer is better than 10 pressed men': A qualitative study into the views of people who plan to opt-out of organ donation.
Not available
S-EPMC7216962 | biostudies-literature
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