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TranscriptomicsDefining the microglia transcriptome during disease progression in ALS transgenic mice
Purpose: We purified spinal cord microglia utilizing percoll gradients and magnetic beads, followed by transcriptome profiling (RNA-seq) to define microglia expression profiles against other neural, immune cell-types. We next observed how the microglial transcriptomes change during activation in the...
ORGANISM(S): Mus musculus 
2013-07-15 | E-GEOD-43366 | biostudies-arrayexpress
UnknownLCMV-mediated loss of virtual memory CD8 T cells yields a functionally enhanced T cell subset.
Not available
S-EPMC12639556 | biostudies-literature
UnknownEnsemble quantitation of absolute metabolite concentrations in T cells reveals conserved features of immunometabolism.
Not available
S-EPMC12259047 | biostudies-literature
UnknownRapid interferon independent expression of IFITM3 following T cell activation protects cells from influenza virus infection.
Not available
S-EPMC6334895 | biostudies-literature
UnknownStaphylococcus aureus infection of mice expands a population of memory γδ T cells that are protective against subsequent infection.
Not available
S-EPMC3979672 | biostudies-literature
UnknownCirculatory antigen processing by mucosal dendritic cells controls CD8(+) T cell activation.
Not available
S-EPMC3858856 | biostudies-literature
UnknownGlucocorticoid-Induced TNF Receptor Family-Related Protein Ligand is Requisite for Optimal Functioning of Regulatory CD4(+) T Cells.
Not available
S-EPMC3909995 | biostudies-literature
UnknownExpansion of an osteopontin-expressing T follicular helper cell subset correlates with autoimmunity in B6.Sle1b mice and is suppressed by the H1-isoform of the Slamf6 receptor.
Not available
S-EPMC3714581 | biostudies-literature
UnknownSLAMF4 Is a Negative Regulator of Expansion of Cytotoxic Intraepithelial CD8+ T Cells That Maintains Homeostasis in the Small Intestine.
Not available
S-EPMC4409516 | biostudies-literature
TranscriptomicsAn intricate interplay between astrocytes and motor neurons in ALS
Amyotrophic Lateral Sclerosis (ALS) results from the selective and progressive degeneration of motor neurons. Although the underlying disease mechanisms remain unknown, glial cells have been implicated in ALS disease progression. Here we examine the effects of glial cell/motor neuron interactions on...
ORGANISM(S): Mus musculus 
2013-02-11 | E-GEOD-43879 | biostudies-arrayexpress
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