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TranscriptomicsTranscription profiling of human bladder cancer cell line TCCSUP over-expressing the transcription factor Oct-4 and control-tansfected cells
Comparison of TCCSUP cancer cells transformed with an EGFP control vector vs transcription factor Oct-4 overexpressed line of TCCSUP cancer cells
ORGANISM(S): Homo sapiens 
2008-09-30 | E-MEXP-1378 | biostudies-arrayexpress
TranscriptomicsComparison of the expression profiles of wild type (WT) and Oct-6-deficient (Oct-6-/-) macrophages in response to poly(I:C) treatment
Identification of target genes of the POU-transcription factor Oct-6 in macrophages after poly(I:C) treatment WT and Oct-6-/- fetal-liver macrophages were treated with poly(I:C) for 8 hours or were left untreated (3 independent expreiments = biological replicates). 200 genes differentially regulated...
ORGANISM(S): Mus musculus 
2010-08-01 | E-GEOD-22691 | biostudies-arrayexpress
ProteomicsUltrasonic-based OCT-removal from solid tumor biopsies.
A new method for proteomic studies of OCT-embedded samples based on ultrasound energy is proposed. The cleaning of OCT from mouse kidney embedded tissues were evaluated through the aid of ultrasound energy, with two different frequencies. Simultaneously, vortex agitation was used as control. The opt...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-06-13 | PXD013164 | Pride
Oct-embedded samples Ultrasound energy Renal oncocytoma Mass spectrometry. Chromophobe renal cell carcinoma Sample treatment 
TranscriptomicsTranscription profiling of mouse fibroblasts to understand the effect of radiation on Oct-1 deficient and wild type mouse strains.
The POU-domain transcription factor Oct-1 is widely expressed in adult tissues and has been proposed to regulate a large group of target genes. Microarray expression profiling was used to evaluate gene expression changes in Oct-1-deficient mouse fibroblasts. A number of genes associated with cellula...
ORGANISM(S): Mus musculus 
2007-09-21 | E-GEOD-2084 | biostudies-arrayexpress
TranscriptomicsSuv4-20h Histone Methyltransferases Promote Neuroectodermal Differentiation by Silencing the Pluripotency-Associated Oct-25 Gene
Post-translational modifications (PTMs) of histones exert fundamental roles in regulating gene expression. During development, groups of PTMs are constrained by unknown mechanisms into combinatorial patterns, which facilitate transitions from uncommitted embryonic cells into differentiated somatic c...
ORGANISM(S): Xenopus laevis 
2013-02-06 | E-GEOD-41256 | biostudies-arrayexpress
GenomicsGenome-wide maps of Sox/Oct partnerships pluripotent and lineage-committed cells
We show here by using genome-wide ChIP-sequencing that lineage segregation involves multiple Sox/Oct partnership. In undifferentiated ES cells Oct4 interacts with Sox2 and both TFs bind on the 'canonical' motif, whereas in cells commited to PrE lineage Oct4 switches from Sox2 to Sox17 interaction an...
ORGANISM(S): Mus musculus 
2013-04-23 | E-GEOD-43275 | biostudies-arrayexpress
TranscriptomicsStemness-related factor Sall4 interacts with transcription factors Oct-3/4 and Sox2 and occupies Oct-Sox elements in mouse embryonic stem cells
A small number of transcription factors, including Oct-3/4 and Sox2, constitute the transcriptional network that maintains pluripotency in embryonic stem (ES) cells. Previous reports suggested that some of these factors form a complex that binds the Oct-Sox element, a composite sequence consisting o...
ORGANISM(S): Mus musculus 
2012-12-28 | E-GEOD-40072 | biostudies-arrayexpress
GenomicsAeromonas dhakensis strain:BAR-OCT | isolate:Environmental
Aeromonas dhakensis strain:BAR-OCT | isolate:Environmental Genome sequencing
PRJNA1211687 | ENA
GenomicsThe self-renewal function of Oct-4 can be replaced by the EWS-OCT-4 fusion protein in embryonic stem cells
The self-renewal function of Oct-4 can be replaced by the EWS-OCT-4 fusion protein in embryonic stem cells
PRJNA1243900 | ENA
TranscriptomicsDifferent N-terminal isoforms of Oct-1 control expression of distinct sets of genes and their high level in cancer cells promotes pro-oncogenic processes
High level of Oct-1 isoforms in cells promotes pro-oncogenic processes Total RNA obtained from Namalwa cell line stably transfected by Oct-1 isoforms: Oct-1A, or Oct-1L or Oct-1X compared to untransfected control Namalwa cells. For each of the experimental conditions, total RNA was extracted from ...
ORGANISM(S): Homo sapiens 
2016-05-14 | E-GEOD-80287 | biostudies-arrayexpress
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