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by using a mass spectrometry-based quantitative proteomics approach, we discovered that OCTR-1 regulates innate immunity by suppressing translation and the unfolded protein response (UPR) pathways at the protein level.
ORGANISM(S): Caenorhabditis elegans 
2016-12-22 | PXD004173 | Pride
RNA sequencing to study the molecular relationships between temperature, aging, and OCTR-1
To gain molecular insights into OCTR-1-dependent longevity responses to temperatures, we employed RNA-seq to compare gene expression in young and old wild-type and octr-1(ok371) animals propagated at different temperatures (15°C, 20°C and 25°C).
ORGANISM(S): Caenorhabditis elegans 
2025-04-30 | GSE252054 | GEO
To provide insights into the mechanism underlying the enhanced immunity of tag-24/octr-1 animals, we used genome microarrays to find clusters of genes commonly misregulated in tag-24 relative to wild-type animals grown on live P. aeruginosa. Gravid adult wild-type and tag-24/octr-1 animals were lys...
ORGANISM(S): Caenorhabditis elegans 
To provide insights into the mechanism underlying the enhanced immunity of tag-24/octr-1 animals, we used genome microarrays to find clusters of genes commonly misregulated in tag-24 relative to wild-type animals grown on live P. aeruginosa.
ORGANISM(S): Caenorhabditis elegans 
2011-04-21 | GSE27867 | GEO
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