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ProteomicsAMBRA1 controls the translation of immune-specific genes in T lymphocytes
T cell receptor (TCR) engagement causes a global cellular response that entrains signaling pathways, cell cycle regulation, and cell death. The molecular regulation of mRNA translation in these processes is poorly understood. During a whole-genome CRISPR screen for regulators of CD95 (Fas/APO-1)-med...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-08 | MSV000096042 | MassIVE
ProteomicsDNA mismatch repair activity of MutLα is regulated by CK2-dependent phosphorylation of MLH1 (S477)
MutLα, a heterodimer consisting of MLH1 and PMS2, is a key player of DNA mismatch repair (MMR), yet little is known about its regulation. In this study, we used mass spectrometry to identify phosphorylated residues within MLH1 and PMS2. The most frequently detected phosphorylated amino acid was seri...
ORGANISM(S): Homo sapiens (Human) 
2018-08-28 | PXD009524 | Pride
Ck2 Phosphorylation Lynch syndrome Dna mismatch repair Mutlα Mlh1 
UnknownT-cell-derived Hodgkin lymphoma has motility characteristics intermediate between Hodgkin and anaplastic large cell lymphoma.
Not available
S-EPMC9189347 | biostudies-literature
UnknownAMBRA1 controls the translation of immune-specific genes in T lymphocytes.
Not available
S-EPMC11536168 | biostudies-literature
UnknownDifferential proteome and phosphoproteome signatures in human T-lymphoblast cells induced by sirolimus.
Not available
S-EPMC6496580 | biostudies-literature
UnknownFetal calf serum heat inactivation and lipopolysaccharide contamination influence the human T lymphoblast proteome and phosphoproteome.
Not available
S-EPMC3280938 | biostudies-literature
UnknownThe RHOA Mutation G17V Does Not Lead to Increased Migration of Human Malignant T Cells but Is Associated with Matrix Remodelling.
Not available
S-EPMC10296629 | biostudies-literature
ProteomicsThe transcription factor TAL1 and the miR-17-92 cluster establish a regulatory loop
A network of gene regulatory factors such as transcription factors and microRNAs establish and maintain the gene expression pattern during hematopoiesis. In this network transcription factors regulate each other and are involved in regulatory loops with microRNAs.The microRNA cluster miR-17-92 is lo...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018052 | Pride
Human Microrna Blood Tal1 Jurkat cells Mir-17-92 Hematopoiesis 
UnknownGenetic lesions in nodular lymphocyte-predominant Hodgkin lymphoma and T cell/histiocyte-rich large B-cell lymphoma identified by whole genome sequencing.
Not available
S-EPMC12380620 | biostudies-literature
UnknownCytokine-responsive T- and NK-cells portray SARS-CoV-2 vaccine-responders and infection in multiple myeloma patients.
Not available
S-EPMC10776400 | biostudies-literature
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