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TranscriptomicsTranscription profiling of zebrafish embryos injected with Ofd1 morphlino compared to wild type
Comparison of Ofd1 morphlino injected zebrafish embryos with wild type
ORGANISM(S): Danio rerio 
2008-12-01 | E-MEXP-1879 | biostudies-arrayexpress
TranscriptomicsOFD1 interacts with the Preinitiation complex of translation and regulates translation of specific targets in the kidney
OFD1 is a centrosomal/basal body protein codified by a transcript that when mutated results in OFD type I (OFDI) syndrome, a pleiotropic disorders associated with ciliary dysfunction. We demonstrate that components of the Preinitiation complex of translation (PIC) colocalize to the centrosome and in...
ORGANISM(S): Mus musculus 
2017-03-15 | E-MTAB-2827 | biostudies-arrayexpress
GenomicsEffect of knockdown OFD1 on gene expression in pancreatic cancer cells
Effect of knockdown OFD1 on gene expression in pancreatic cancer cells
PRJNA1190360 | ENA
TranscriptomicsEffect of knockdown OFD1 on gene expression in pancreatic cancer cells
PARP inhibitors (PARPi) have demonstrated efficacy in treating human cancers with BRCA1 or BRCA2 gene mutations, which are present in only a small portion of breast, ovarian, prostate, and pancreatic cancers. In this study, we discovered that OFD1 is highly expressed in pancreatic cancer and is asso...
ORGANISM(S): Homo sapiens 
2025-06-08 | GSE282746 | GEO
UnknownConservation of OFD1 Protein Motifs: Implications for Discovery of Novel Interactors and the OFD1 Function.
Not available
S-EPMC11818881 | biostudies-literature
ProteomicsThe ternary complex CEP90, FOPNL and OFD1 specifies the future location of centriolar distal appendages, and promotes their assembly
Cilia assembly starts with centriole to basal body maturation, migration to the cell surface and docking to the plasma membrane. The basal body docking process involves the interaction of both the distal end of the basal body and the transition fibers (or mature distal appendages), with the plasma m...
ORGANISM(S): Homo sapiens (Human) 
2022-07-20 | PXD028740 | Pride
Pibf1 Kiaa0753 Centriolar Ofd1 Ofip For20 Cep90 Mnr Centrosomal Fopnl 
UnknownRegional selection acting on the OFD1 gene family.
Not available
S-EPMC3193505 | biostudies-literature
UnknownAutistic Behavior as Novel Clinical Finding in OFD1 Syndrome.
Not available
S-EPMC9957277 | biostudies-literature
Genomics
RNA-seq in blood to detect OFD1 expression
PRJNA914088 | ENA
UnknownOFD1, as a Ciliary Protein, Exhibits Neuroprotective Function in Photoreceptor Degeneration Models.
Not available
S-EPMC4873209 | biostudies-literature
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