Sort   by:  
 Page size 
Lung cancer is the leading cause of cancer-related death and poses a direct health threat in our country. Non-small cell lung cancer (NSCLC) represents the majority of lung cancer. Difficulty in early diagnosis and metastasis are the major cause of death of NSCLC patients. However, the molecular mec...
ORGANISM(S): Homo sapiens 
2023-10-13 | GSE218949 | GEO
Eukaryotic genome is compartmentalized into structural and functional domains. One of the concepts of higher order organization of chromatin posits that the DNA is organized in constrained loops that behave as independent functional domains. A predominantly ribo-proteinaceous nucleoskeleton, termed ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-10-25 | PXD031279 | Pride
Cilia assembly starts with centriole to basal body maturation, migration to the cell surface and docking to the plasma membrane. The basal body docking process involves the interaction of both the distal end of the basal body and the transition fibers (or mature distal appendages), with the plasma m...
ORGANISM(S): Homo sapiens (Human) 
2022-07-20 | PXD028740 | Pride
The molecular mechanism of microtubule-binding protein CEP20 in regulating invasion and metastasis of non-small cell lung cancer
Cytotoxic stress activates stress-activated kinases, initiates adaptive mechanisms, including the unfolded protein response (UPR) and autophagy, and induces programmed cell death. Fatty acid unsaturation prevents cytotoxic stress but the mechanisms are diffuse. We investigated changes in the proteom...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-06 | PXD025396 | Pride
Sort   by:  
 Page size