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ProteomicsSubfractionation of Nuclear Matrix (NuMat)
NuMat is a residual structure resistant to solubilization by nucleases, detergents, and salt solutions that retains the morphology of the nucleus. Purported to be the basis of nuclear architecture, it has remained further undissected. We use a chaotrope to subfractionate the nuclear matrix and decip...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-10-25 | PXD031296 | Pride
Nuclear organization Nuclear matrix Drosophila melanogaster 
ProteomicsFixed and unalterable Matrix Associated Regions in Drosophila melanogaster genome
Eukaryotic genome is compartmentalized into structural and functional domains. One of the concepts of higher order organization of chromatin posits that the DNA is organized in constrained loops that behave as independent functional domains. A predominantly ribo-proteinaceous nucleoskeleton, termed ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-10-25 | PXD031279 | Pride
Mars Numat Development Drosophila Nuclear matrix 
ProteomicsIdentification of evolutionarily conserved nuclear matrix proteins and their prokaryotic origins
Compared to prokaryotic cells, a typical eukaryotic cell is much more complex along with its endomembrane system and membrane-bound organelles. Although the endosymbiosis theories convincingly explain the evolution of membrane-bound organelles such as mitochondria and chloroplasts, very little is un...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) Drosophila melanogaster (Fruit fly) 
2021-01-26 | PXD012926 | Pride
Core nuclear matrix proteome Nuclear evolution Nuclear matrix Nucleoskeleton Nuclear architecture 
ProteomicsComparison of Nuclear Matrix and Mitotic Chromosome Scaffold proteins in Drosophila S2 cells – Transmission of hallmarks of nuclear organization through mitosis
During open mitosis chromatin condenses to form chromosomes and decondenses post-mitotically to re-occupy their designated nuclear territory in a precisely lineage specific manner. This necessitates that features of nuclear architecture persist through mitosis. Here we present a proteomic study, whi...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2018-07-17 | PXD008404 | Pride
Nuclear matrix Drosophila melanogastor S2 cells Nuclear architecture Mitotic chromosome scaffold Mitosis 
ProteomicsDrosophila melanogaster nuclear matrix proteome
Nucleus is a highly structured organelle and contains many functional compartments. While the structural basis for this complex spatial organization of compartments is unknown, a major component of this organization is likely to be the non-chromatin scaffolding called nuclear matrix (NuMat). Exp...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2011-05-05 | PRD000255 | Pride
UnknownBiochemical Deconstruction and Reconstruction of Nuclear Matrix Reveals the Layers of Nuclear Organization.
Not available
S-EPMC10687341 | biostudies-literature
UnknownComparison of Nuclear Matrix and Mitotic Chromosome Scaffold Proteins in Drosophila S2 Cells-Transmission of Hallmarks of Nuclear Organization Through Mitosis.
Not available
S-EPMC6166678 | biostudies-literature
UnknownStructural and developmental dynamics of Matrix associated regions in Drosophila melanogaster genome.
Not available
S-EPMC9597980 | biostudies-literature
UnknownIn situ Nuclear Matrix preparation in Drosophila melanogaster enabling genetic analysis of the nuclear architecture.
Not available
S-EPMC9117923 | biostudies-literature
UnknownIn situ nuclear matrix preparation in Drosophila melanogaster embryos/tissues and its use in studying the components of nuclear architecture.
Not available
S-EPMC8896195 | biostudies-literature
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