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MetabolomicsMetabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice
It was recently demonstrated in mice that knockout of the flavin-containing monooxygenase 5 gene, Fmo5, slows metabolic ageing via pleiotropic effects. We have now used an NMR-based metabonomics approach to study the effects of ageing directly on the metabolic profiles of urine and plasma from male,...
2018-06-20 | MTBLS667 | MetaboLights
TranscriptomicsGlucosylated hydroxymethyluracil (DNA base J) prevents transcriptional read-through in Leishmania
Some T's in nuclear DNA of trypanosomes and Leishmania are hydroxylated and glucosylated to yield base J (?-D-glucosyl-hydroxymethyluracil). In Leishmania about 99% of J is located in telomeric repeats. We show here that most of the remaining J is located at chromosome-internal RNA Polymerase II ter...
ORGANISM(S): Leishmania major 
2011-10-15 | E-GEOD-32976 | biostudies-arrayexpress
GenomicsAllium cepa strain:OH-1
Allium cepa OH-1 Transcriptome Sequencing
PRJNA175449 | ENA
GenomicsThe In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci
The critical initial step in V(D)J recombination, binding of RAG1 and RAG2 to recombination signal sequences flanking antigen receptor V, D, and J gene segments, has not previously been characterized in vivo. Here we demonstrate that RAG protein binding occurs in a highly focal manner to a small reg...
ORGANISM(S): Mus musculus 
2010-04-19 | E-GEOD-21207 | biostudies-arrayexpress
GenomicsMouse spleen: Histone modification patterns in spleens from wild type and leukemic mice
ChIP-Seq for H3K4me3 and H3K27me3 in wild type spleens and spleens from mice having deletion of RBP-J in cells of the renin lineage, which results in B-cell leukemia. Examination of 2 different histone modifications in wild type and mutant spleens.
ORGANISM(S): Mus musculus 
2014-02-17 | E-GEOD-46566 | biostudies-arrayexpress
TranscriptomicsDrosophila OSS cell small RNA libraries
High-throughput sequencing of Drosophila melanogaster small RNAs from OSS cells. total RNA, ~18-26nt RNAs isolated using PAGE, ligation to adapters requires 5' monophosphate and 3' OH For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Page...
ORGANISM(S): Drosophila melanogaster 
2009-06-08 | E-GEOD-15378 | biostudies-arrayexpress
UnknownSemi-synthesis and insecticidal activity of spinetoram J and its D-forosamine replacement analogues.
Not available
S-EPMC6142758 | biostudies-literature
UnknownA semisynthesis of 3'-O-ethyl-5,6-dihydrospinosyn J based on the spinosyn A aglycone.
Not available
S-EPMC5727846 | biostudies-literature
UnknownSerum 25-hydroxyvitamin D is associated with stroke history in a reverse J-shape.
Not available
S-EPMC9851395 | biostudies-literature
UnknownJ-domain Proteins form Binary Complexes with Hsp90 and Ternary Complexes with Hsp90 and Hsp70.
Not available
S-EPMC10527347 | biostudies-literature
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