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TranscriptomicsTranscription profiling of macrophages derived from WT and Vdr dificient mice after stimulation with IFNgamma and/or 1alpha,25(OH)2D3 to study molecular mechanisms of macrophage activation
Gene expression profiling of macrophages derived from WT and Vdr deficient mice after stimulation with IFNgamma and/or 1alpha,25(OH)2D3
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2421 | biostudies-arrayexpress
TranscriptomicsTranscription profiling Saccharomyces cerevisiae xylose metabolism
In the present study transcriptome and proteome of recombinant, xylose-utilising S. cerevisiae grown in aerobic batch cultures on xylose were compared with glucose-grown cells both in glucose repressed and derepressed states. The aim was to study at genome-wide level how signalling and carbon catabo...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-26 | E-GEOD-12890 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of spinal cords from B10.PL mice with severe (stage 2.5-3) experimental autoimmune encephalomyelitis treated with placebo or 1,25-dihydroxyvitamin D3 to study the molecular mechanism of the compound.
B10.PL mice with severe (stage 2.5-3) experimental autoimmune encephalomyelitis were treated with placebo or 200 ng 1,25(OH)2D3. Six hours later, the spinal cords were harvested and mRNA was extracted for microarray analysis. Naive mice serve as controls. Individual samples were hybridized to ind...
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-842 | biostudies-arrayexpress
MetabolomicsExtracellular reef metabolites across the protected Jardines de la Reina, Cuba reef-system

Coral reef ecosystems are incredibly diverse marine biomes that rely on nutrient cycling by microorganisms to sustain high productivity in generally oligotrophic regions of the ocean. Understanding the composition of extracellular reef metabolites in seawater, the small organic molecules that ser...

2020-11-30 | MTBLS1820 | MetaboLights
MetabolomicsAmino Acid Metabolism is Significantly Altered at the Time of Admission in Hospital for Severe COVID-19 Patients: Findings from Longitudinal Targeted Metabolomics Analysis

The heterogeneity in severity and outcome of COVID-19 cases points out the urgent need for early molecular characterization of patients followed by risk-stratified care. The main objective of this study was to evaluate the fluctuations of serum metabolomic profiles of COVID-19 patients with sever...

2022-08-23 | MTBLS3852 | MetaboLights
TranscriptomicsComparison of whole brain expression data between selectively bred P and NP, alcohol naïve rats
Gene expression was analyzed in brains of 4 male selectively-bred alcohol-preferring (P) rats (generation 63) and 3 male alcohol non-preferring (NP) rats (generation 62) that were obtained from Dr. Richard L. Bell, Indiana University School of Medicine, Indianapolis, IN. These rats had never been e...
ORGANISM(S): Rattus norvegicus 
2011-04-19 | E-GEOD-15764 | biostudies-arrayexpress
TranscriptomicsResponse of ethanologenic E coli strains LY180 and EMFR9 to furfural
The data explore the transcriptional response of strain LY180 and the furfural-resistant derivative EMFR9 to 0.5 g/L furfural LY180 and EMFR9 and differences in their expression profiles are described in Miller, E. N., L. R. Jarboe, L. P. Yomano, S. W. York, K. T. Shanmugam, and L. O. Ingram. 2009. ...
ORGANISM(S): Escherichia coli 
2010-05-06 | E-GEOD-17786 | biostudies-arrayexpress
TranscriptomicsThe transcriptomic response of E. coli to triclosan exposure
The gene expression profile of E. coli K-12 MG1655 grown in minimal medium treated with 0.12 mg/L of the biocide triclosan has been analysed using whole genome oligonucleotide microarrays. "Control" RNA was isolated from three independently grown 50ml MOPS minimal media cultures of E. coli K-12 MG16...
ORGANISM(S): Escherichia coli 
2010-10-08 | E-GEOD-15059 | biostudies-arrayexpress
TranscriptomicsColonization, luminescence, and autoinducer effects on host transcription during development of squid-vibrio association
The light-organ symbiosis between the squid Euprymna scolopes and the luminous bacterium Vibrio fischeri offers the opportunity to decipher the hour-by-hour events that occur during the natural colonization of an animal's epithelial surface by its microbial partners. To determine the genetic basis o...
ORGANISM(S): Euprymna scolopes 
2008-11-10 | E-GEOD-13533 | biostudies-arrayexpress
TranscriptomicsRNA expression for ethanologenic E coli strains LY180 and LY180 del yqhC in the absence and presence of furfural
The data explore the transcription of strain LY180 and the yqhC deletion mutant LY180 del yqhC without and with 0.5 g/L furfural. LY180 and LY180 del yqhC are described in Turner, PC, EN Miller, LR Jarboe, P Pharkya, KT Shanmugam, and LO Ingram. 2009. Escherichia coli YqhC regulates transcription of...
ORGANISM(S): Escherichia coli 
2010-08-24 | E-GEOD-17788 | biostudies-arrayexpress
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