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Background: In a recent intervention study, the daily supplementation with 200mg monomeric and oligomeric flavanols (MOF) from grape seeds for 8 weeks revealed a vascular health benefit in male smokers. The objective of the present study was to determine the impact of MOF consumption on the gene exp...
ORGANISM(S): Homo sapiens 
Caseinolytic protease P (ClpP) is a tetradecameric peptidase which assembles with chaperones such as ClpX to gain proteolytic activity. Acyldepsipeptides (ADEPs) represent small molecule mimics of ClpX, which bind into hydrophobic pockets on the apical site of the complex and thereby induce activati...
ORGANISM(S): Staphylococcus aureus 
2020-05-26 | PXD015244 | Pride
Background: In a recent intervention study, the daily supplementation with 200 mg monomeric and oligomeric flavanols (MOF) from grape seeds for 8 weeks revealed a vascular health benefit in male smokers. The objective of the present study was to determine the impact of MOF consumption on the gene ex...
ORGANISM(S): Homo sapiens 
A shift in PKM2 oligomeric state instructs adipocyte inflammatory potential
In maize, two plastidic NADP-malic enzyme (C4-NADP-ME) isoforms are present: C4-NADP-ME and nonC4-NADP-ME, each with distinct kinetic and structural features. To investigate the differences in oligomeric states of C4- and nonC4-NADP-ME in plant tissues, we analyzed extracts of maize from etiolated l...
ORGANISM(S): Zea mays (Maize) 
2026-05-25 | PXD059557 | Pride
The tumor suppressor protein p53 is a transcription factor that is referred to as the “guardian of the genome” and plays an important role in cancer development. P53 is active as a tetramer; the S100β homodimer binds to the intrinsically disordered C-terminus of p53, affecting its transcriptional ac...
ORGANISM(S): Escherichia coli 
2022-10-14 | PXD029914 | Pride
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