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TranscriptomicsPregnancy changes expression in peripheral blood mononuclear cells of Multiple Sclerosis (MS) patients
Background: pregnancy is associated with reduced activity of multiple sclerosis (MS). However, the biological mechanisms underlying this pregnancy-related decrease in disease activity are poorly understood. This data series contains the subset of data used to generate a MS signature comparing female...
ORGANISM(S): Homo sapiens 
2010-01-10 | E-GEOD-17410 | biostudies-arrayexpress
TranscriptomicsGene expression and epigenetic profiling of CD34+ hematopoietic progenitor cells in multiple sclerosis patients (expression)
Intense immunosuppression followed by autologous hematopoietic stem cell transplantation (aHSCT) is a potential treatment for patients suffering from aggressive multiple sclerosis (MS). However it remains unresolved whether autologous CD34+ hematopoietic progenitor cells of MS patients show gene exp...
ORGANISM(S): Homo sapiens 
2012-09-05 | E-GEOD-27688 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of mouse embryonic stem cells treated with MS-275
This study describes transcriptome profiling of mouse ES cells treated with MS-275. We included RNA-Seq of ds_cDNA synthesized from double poly(A) selected mRNA RNA-Seq profiling on mouse ES cells treated with MS-275
ORGANISM(S): Mus musculus 
2014-03-28 | E-GEOD-45909 | biostudies-arrayexpress
TranscriptomicsTranscript copy number estimation using a mouse whole-genome oligonucleotide microarray (WGA 2.1 Spike Test)
E12.5 mouse whole embryo, E12.5 placenta, embryonic stem (ES) cells, and trophoblast stem (TS) cells were compared on a novel microarray design to validate the system. The in situ-synthesized 60-mer oligonucleotide microarray platform contains approximately 44,000 DNA features, and was designed to ...
ORGANISM(S): Mus musculus 
2005-10-28 | E-GEOD-3509 | biostudies-arrayexpress
ProteomicsComprehensive Evaluation of RNases, Nano-Flow HILIC Chromatography, and Mass Spectrometry for Shotgun RNomics of Native RNA
RNA modifications play crucial roles in regulating cellular processes, but comprehensive mapping of the human RNome still remains limited by technological challenges. Mass spectrometry is a valuable tool to analyse RNA modifications and complementing sequencing-based analysis. Current MS-based oligo...
ORGANISM(S): Escherichia coli 
2026-09-07 | PXD070755 | Pride
Rnase Rnome Oligonucleotide ms Hilic Nano-flow Lc-ms/ms 
ProteomicsE.coli total RNA digests higer-collision dissociation energies test in LC-MS/MS
Four open-source software suites for the analysis of oligonucleotide data from tandem MS have been reported. These tools are all based on matching theoretical spectral libraries generated by silico digestion. While some software publications have included simple comparisons with previously published...
ORGANISM(S): Escherichia coli 
2026-03-11 | PXD075509 | Pride
E.coli rna Hcd Oligonucleotide Lc-ms/ms 
ProteomicsE.coli total RNA RNase T1 and A digests LC-MS/MS
Four open-source software suites for the analysis of oligonucleotide data from tandem MS have been reported. These tools are all based on matching theoretical spectral libraries generated by silico digestion. While some software publications have included simple comparisons with previously published...
ORGANISM(S): Escherichia coli 
2026-03-09 | PXD075396 | Pride
E.coli rna Oligonucleotide Lc-ms/ms 
TranscriptomicsTranscription signature of Multiple Sclerosis in peripheral blood mononuclear cells.
Background: pregnancy is associated with reduced activity of multiple sclerosis (MS). However, the biological mechanisms underlying this pregnancy-related decrease in disease activity are poorly understood. This data series contains the subset of data used to generate a MS signature comparing female...
ORGANISM(S): Homo sapiens 
2010-01-10 | E-GEOD-17393 | biostudies-arrayexpress
TranscriptomicsImproved detection of global copy number variation using high density, non-polymorphic oligonucleotide probes
Goal: To identify copy number variation in normal individuals using high density, non-polymorphic oligonucleotide probes Background DNA sequence diversity within the human genome may be more greatly affected by copy number variations (CNVs) than single nucleotide polymorphisms (SNPs). Although the ...
ORGANISM(S): Homo sapiens 
2008-04-24 | E-GEOD-9053 | biostudies-arrayexpress
TranscriptomicsGene expression and epigenetic profiling of CD34+ hematopoietic progenitor cells in multiple sclerosis patients (miRNA)
Intense immunosuppression followed by autologous hematopoietic stem cell transplantation (aHSCT) is a potential treatment for patients suffering from aggressive multiple sclerosis (MS). However it remains unresolved whether autologous CD34+ hematopoietic progenitor cells of MS patients show gene exp...
ORGANISM(S): Homo sapiens 
2012-09-05 | E-GEOD-27690 | biostudies-arrayexpress
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