Sort   by:  
 Page size 
ProteomicsPolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons
A GGGGCC repeat expansion in C9orf72 is the most common genetic cause of ALS and FTD (C9ALS/FTD). Dipeptide repeat (DPR) proteins, generated by translation of the expanded repeat, are a major pathogenic feature of C9ALS/FTD pathology, but their physiological impact has yet to be fully determined. He...
ORGANISM(S): Mus musculus (Mouse) 
2024-03-04 | PXD047502 | Pride
Tgf-β Collagen vi Frontotemporal dementia Amyotrophic lateral sclerosis Proteomics Col6a1 C9orf72 Extracellular matrix 
UnknownMolecular mechanisms of chaperone-directed protein folding: Insights from atomistic simulations.
Not available
S-EPMC10895457 | biostudies-literature
ProteomicsPurification, Structural Characterization, and Anticandidal Activity of a Chitin-binding Peptide with high Similarity to Hevein and Endochitinase Isolated from Pepper Seeds
Antimicrobial peptides (AMPs) are a group of molecules that occur naturally in all living organisms and help them to defend against various pathogens, including fungi, bacteria and viruses (Gan et al., 2021). AMPs have a low molecular mass (~2-50 amino acids), are rich in hydrophobic amino acids and...
ORGANISM(S): Capsicum chinense 
2024-10-17 | PXD054607 | Pride
Antimicrobial peptides  capsicum chinense  fungi  candida albicans  c. tropicalis 
TranscriptomicsInterference of hemozoin formation in Schistosoma mansoni by quinine reduces experimental schistosomiasis
Background: The parasitic trematode Schistosoma mansoni is one of the major causative agents of human schistosomiasis, which afflicts 200 million people worldwide. Praziquantel is still the only drug used for schistosomiasis treatment and reduction in drug efficiency has prompting the search for ne...
ORGANISM(S): Schistosoma mansoni 
2010-06-24 | E-GEOD-14751 | biostudies-arrayexpress
TranscriptomicsToxicogenomic analysis of rural and urban air particles
Atmospheric particulate matter (PM) is a recognized risk factor for the global burden of disease in human populations. We are presenting here the application of toxicogenomics in the evaluation of the toxic effects of organic content of atmospheric particle matter (PM), from urban and rural environm...
ORGANISM(S): Danio rerio 
2015-10-26 | E-GEOD-53522 | biostudies-arrayexpress
UnknownRAF inhibitors activate the integrated stress response by direct activation of GCN2.
Not available
S-EPMC12623982 | biostudies-literature
UnknownThe landscape of cancer-rewired GPCR signaling axes.
Not available
S-EPMC11099383 | biostudies-literature
TranscriptomicsDynamic mRNA gene expression following a rapamycin treatment
Dynamic mRNA gene expression from the wildtype YSBN6 during a rapamycin treatment (rapamycin-induced downshift). Rapamycin was added to yeast cells growing exponentially on glutamine as sole nitrogen source. A sample was taken at steady-state 10 minutes before , and then 3, 7, 10, 14, 24, 56 and 120...
ORGANISM(S): Saccharomyces cerevisiae 
2015-04-07 | E-GEOD-54851 | biostudies-arrayexpress
TranscriptomicsDynamic mRNA gene expression during a nutritional upshift from proline to glutamine
Dynamic mRNA gene expression from the wildtype YSBN6 during a nutritional upshift from proline to glutamine. Glutamine was added to yeast cells growing exponentially on proline as the sole nitrogen source. A sample was taken at steady-state 10 minutes before the shift, and then 3, 7, 10, 14, 24, 56 ...
ORGANISM(S): Saccharomyces cerevisiae 
2015-04-07 | E-GEOD-54844 | biostudies-arrayexpress
UnknownPolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons.
Not available
S-EPMC11001582 | biostudies-literature
Sort   by:  
 Page size