The unsupervised hierarchical clustering analysis of the 122 miRNAs revealed a marked separation of mtOLK from OLK, suggesting that this differential expression profile might be used as a possible phenotypic discriminator between OLK and mtOLK.Comparing with OLK, 72 up-regulated and 50 down-regulate...
The unsupervised hierarchical clustering analysis of the 122 miRNAs revealed a marked separation of mtOLK from OLK, suggesting that this differential expression profile might be used as a possible phenotypic discriminator between OLK and mtOLK.Comparing with OLK, 72 up-regulated and 50 down-regulate...
Oral leukoplakia (OLK), a recognized oral potentially malignant disorder, demonstrates significant susceptibility to malignant transformation into oral squamous cell carcinoma (OSCC). This study aimed to investigate the involvement of migrasomes, novel intercellular communication organelles, in the ...
6 pairs of OLK tissues and normal oral mucusal (NOM) tissues were obtained to detect circRNAs expression.The profile data showed that 366 circRNAs were significantly dysregulated in the OLK tissues, including 65 upregulated and 301 downregulated circRNA transcripts.There are 28 circRNAs were discove...
Objective This study aimed to investigate the expression and clinical significance of N6-methyladenosine (m6A) modification of circular RNA (circRNA) in oral leukoplakia (OLK) and oral squamous carcinoma cell (OSCC) tissues. Methods Using methylation RNA immunoprecipitation high-throughput sequencin...