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In spite of 40 years of control efforts, onchocerciasis (river blindness) remains one of the most important neglected tropical diseases, with 17 million people affected. The aetiological agent, Onchocerca volvulus, is a filarial nematode with a complex lifecycle involving several distinct stages in ...
ORGANISM(S): Onchocerca ochengi (Filarial nematode worm) 
2016-05-31 | PXD002889 | Pride
We report the presence of Onchocerca ochengi and O. volvulus derived small RNAs in bovine nodule fluids and human serum and plasma, respectively. Further comparisons with other related filarial nematodes like Litomosoides sigmodontis and Dirofilaria immitis reveal common and distictive signatures as...
ORGANISM(S): Bos taurus 
Filarial nematodes possess glutathione transferases (GSTs), ubiquitous enzymes with potential to detoxify xenobiotic and endogenous substrates, and modulate the host immune system, which may aid worm infection establishment, maintenance and survival in the host. Here we have identified and character...
ORGANISM(S): Onchocerca ochengi (Filarial nematode worm) 
2020-05-26 | PXD013440 | Pride
The genome of Wolbachia endosymbiont of Onchocerca ochengi
Onchocerca ochengi overview
Wolbachia endosymbiont of Onchocerca ochengi str. Adamawa_Cameroon Genome sequencing
Whole genome resequencing of Onchocerca ochengi individuals
Onchocerca ochengi genomic assembly
Genomic assembly of nematode Onchocerca ochengi, as part of the 50 Helminth Genomes Initiative sequencing of the parasitic worms that have the greatest impact on human, agricultural and veterinary disease and cause significant global health issues particularly in the developing world, or those used ...
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