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MetabolomicsUnique metabolic regulation of micromeres contributes to their inductive signaling in the sea urchin embryo

In many multicellular organisms, a group of cells called organizers plays critical roles by sending signals to adjacent cells and controlling patterning events such as embryogenesis and tissue morphogenesis. Recent studies suggest that these organizers or inductive cells facilitate the downstream...

2025-07-07 | MTBLS5017 | MetaboLights
MetabolomicsEffects of hypoxic preconditioning on neuroblastoma tumour oxygenation and metabolic signature in a chick embryo model
Hypoxia episodes and areas in tumours have been associated with metastatic dissemination and poor prognosis. Given the link between tumour tissue oxygen levels and cellular metabolic activity, we hypothesised that the metabolic profile between metastatic and non-metastatic tumours would reveal poten...
2018-08-13 | MTBLS541 | MetaboLights
MetabolomicsJiawei Shoutai Pill Promotes Embryo Implantation via PPAR Signaling and Endometrial Microbiota Remodeling: An Integrative Multi-Omics Study
Background: Recurrent implantation failure (RIF) remains a major barrier to successful assisted reproductive technology, given the lack of effective, mechanism-informed interventions to enhance endometrial receptivity. Jiawei Shoutai Wan (pills) (JWSTW), a modified formulation of the classic Shoutai...
2026-03-31 | MTBLS14199 | MetaboLights
TranscriptomicsValidation of rapid embryo tracking using cell-free fetal DNA enriched from maternal circulation at 9 weeks gestation
Embryo DNA fingerprinting represents an important tool for tracking embryo-specific outcomes after multiple embryo transfer during IVF. The situation in which 2 embryos are transferred and only one implants represents a unique opportunity for the most well-controlled comparison of competent and inc...
ORGANISM(S): Homo sapiens 
2011-04-14 | E-GEOD-26404 | biostudies-arrayexpress
TranscriptomicsBovine pre-transfer endometrium and embryo transcriptome fingerprints as predictors of pregnancy success after embryo transfer (endometrial study)
The aberrant gene expression in the uterine endometrium and embryo has been the major causes of pregnancy failure in cattle. Therefore, selecting cows having adequate endometrial receptivity and embryos of better developmental competence based on the gene expression could increase the number of calv...
ORGANISM(S): Bos taurus 
2010-04-07 | E-GEOD-20974 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human, mouse, Bos taurus embryo
The process of early development of mammals is subtly and accurately controlled by the regulation networks of embryo cells. Time course expression data measured at different stages during early embryo development process can give us valuable information by revealing the dynamic expression patterns o...
ORGANISM(S): Bos taurus 
2009-10-02 | E-GEOD-18290 | biostudies-arrayexpress
GenomicsA unique regulatory phase of DNA methylation in the early mammalian embryo
DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly accepted that the paternal genome is actively depleted of global cytosine methylation at fertilization, followed by passive depletion that reaches a minimum at the blastocyst stage. However, this model is based on limit...
ORGANISM(S): Mus musculus 
2012-03-28 | E-GEOD-34864 | biostudies-arrayexpress
ProteomicsPhospoproteome along the dorso-ventral axis of the early Drosophila embryo
The initially homogeneous epithelium of the early Drosophila embryo differentiates into regional subpopulations with different behaviours and physical properties that are needed for morphogenesis. The factors at top of the genetic hierarchy that control these behaviours are known, but many of their ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-10-01 | PXD046192 | Pride
Phosphorylation Embryo Drosophila Lc-ms/ms 
ProteomicsProteomic analysis of somatic embryo development in Musa spp. cv. Grand Naine (AAA)
Somatic embryos are very much similar to zygotic counterparts in many morphological aspects and the somatic embryos are derived from somatic cells by undergoing various metabolic regulations. The somatic embryos have been used in artificial seed technology, genetic engineering and germplasm conserva...
ORGANISM(S): Musa acuminata AAA Group 
2020-03-16 | PXD015551 | Pride
Proteomics Development Somatic embryos Banana 
TranscriptomicsTranscription profiling of Drosophila embryo - comparison of Dorsal threshold outputs
Whole-Genome Analysis of Dorsal-Ventral Patterning in the Drosophila Embryo. The maternal Dorsal regulatory gradient initiates the differentiation of several tissues in the early Drosophila embryo. Whole-genome microarray assays identified as many as 40 new Dorsal target genes, which encode a broad ...
ORGANISM(S): Drosophila melanogaster 
2008-06-20 | E-GEOD-86 | biostudies-arrayexpress
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