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Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition
The oocyte-to-embryo transition (OET) is thought to be mainly driven by post-transcriptional gene regulation. However, expression of both RNAs and proteins during the OET has not been comprehensively assayed. Furthermore, specific molecular mechanisms that regulate gene expression during OET are lar...
ORGANISM(S): Caenorhabditis elegans 
Distinct transcriptome, translatome, and proteome reprogramming during the oocyte-to-embryo transition
A long-standing question in developmental and reproductive biology is when the mammalian embryo becomes sufficiently distinct from its oocyte precursor. Myriads of studies examined the messenger RNAs that change during the oocyte-to-embryo transition, whereas proteins have been much less studied, in...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-19 | PXD035570 | Pride
20S proteasome-regulated proteostasis in ELVAs is critical for oocyte-to-embryo transition and female fertility
The APC/CFZY-1/Cdc20 complex coordinates with OMA-1 to regulate the oocyte-to-embryo transition in C. elegans
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