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TranscriptomicsTranscriptional analysis (nCounter Human Immunology v2 Panel) of A549 cells with HMGB1 knockdown and infected with WT or attenuated mutant Dengue virus 2 strains
HMGB1 were silence in A549 cells using siRNA targeting.These A549 cells were then infected with WT Dengue virus 2 and its attenuated mutants (generated using infectious clone construction with site-directed mutagenesis) to better understand the gene expression changes induced by these different atte...
ORGANISM(S): Homo sapiens 
2026-05-14 | E-MTAB-16204 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of primary human monocyte-derived dendritic cells (moDCs) infected with WT and attenuated mutant Dengue virus 2 strains
Primary human monocytes were isolated and differentiated into moDCs. These moDCs were infected with WT Dengue virus 2 and its attenuated mutants (generated using infectious clone construction with site-directed mutagenesis) to better understand the gene expression changes induced by these different ...
ORGANISM(S): Homo sapiens 
2026-04-14 | E-MTAB-16201 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis (nCounter Human Immunology v2 Panel) of primary human monocyte-derived dendritic cells (moDCs) infected with WT and attenuated mutant Dengue virus 2 strains
Primary human monocytes were isolated and differentiated into moDCs. These moDCs were infected with WT Dengue virus 2 and its attenuated mutants (generated using infectious clone construction with site-directed mutagenesis) to better understand the gene expression changes induced by these different ...
ORGANISM(S): Homo sapiens 
2026-04-14 | E-MTAB-16202 | biostudies-arrayexpress
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