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ProteomicsPerformance of the Orbitrap Fusion Lumos Tribrid in single-shot analyses of human samples
One of the major additions in mass spectrometry technology has been the irruption of the Orbitrap mass analyzer, which has boosted the proteomics analyses of biological complex samples since its introduction. Here we assessed the performance of the new generation Orbitrap Fusion Lumos Tribrid mass s...
ORGANISM(S): Homo sapiens (Human) 
2017-03-09 | PXD004940 | Pride
Protein quantitation Orbitrap fusion lumos Mass spectrometry Phosphorylation Protein identification 
MetabolomicsPhenomic and multiomic characterisation of microsatellite-stable colorectal cancer reveals novel biology and targets of vulnerability

Integrating data from approximately 2,000 tumour samples, corresponding to ~4,500 platform-specific multiomic sample profiles, and 195,246 single cells/nuclei from diverse in-house and publicly available datasets, single-to-integrated multiomic and clinical phenome data fusion analysis uncovers t...

2026-09-15 | MTBLS15127 | MetaboLights
UnknownProduction of Over 27 000 Peptide and Nearly 4400 Protein Identifications by Single-Shot Capillary-Zone Electrophoresis-Mass Spectrometry via Combination of a Very-Low-Electroosmosis Coated Capillary, a Third-Generation Electrokinetically-Pumped Sheath-Flow Nanospray Interface, an Orbitrap Fusion Lumos Tribrid Mass Spectrometer, and an Advanced-Peak-Determination Algorithm.
Not available
S-EPMC6508074 | biostudies-literature
ProteomicsProbing the Sensitivity of the Lumos Mass Spectrometer by analyzing varying amounts of whole cell extracts
PROJECT DESCRIPTION The Orbitrap Fusion Lumos mass spectrometer has recently been shown to have better fragmentation and detection than its predecessors. Previous studies using a HeLa digest analyzed on the Lumos mass spectrometer have reported the number of peptides and proteins identified by rever...
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2018-04-19 | MSV000082296 | MassIVE
ProteomicsProbing the Sensitivity of the Lumos Mass Spectrometer using a Standard Reference Protein in a Complex Background
we determined the sensitivity of the Lumos mass spectrometer using the NIST monoclonal antibody reference material at various concentrations to detect its peptides in a background of S. cerevisiae whole cell lysate, which was kept at a constant concentration.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-09-12 | PXD009441 | Pride
Data-dependent acquisition Orbitrap lumos Mass spectrometry Proteomics Limit of detection Sensitivity 
MetabolomicsXuezhikang Ameliorating Non-Alcoholic Fatty Liver Disease via the Gut Microbiota-Metabolite-Ferroptosis Axis: A Multi-Omics Study
Objective: This study investigated the therapeutic mechanism by which Xuezhikang (XZK) alleviates non-alcoholic fatty liver disease (NAFLD) in mice, with a specific focus on the interplay between the gut microbiota, metabolic alterations, and hepatic ferroptosis. Methods: An NAFLD mouse model was in...
2026-06-16 | MTBLS14743 | MetaboLights
ProteomicsSingle shot CZE-MS/MS for phosphoproteomics
The dependence of capillary zone electrophoresis separations on the charge state of analyte is useful for the analysis of many post-translational modifications in proteins. In this work, we coupled CZE to an Orbitrap Fusion Lumos Tribrid platform with advanced peak determination algorithm for phosph...
ORGANISM(S): Mus musculus (Mouse) 
2019-06-13 | PXD012888 | Pride
Cze Phosphoproteomics Orbitrap fusion lumos tribrid Advanced peak determination algorithm 
MetabolomicsComposition and consumption of dissolved organic carbon in seawater under sea ice

Polar regions are an under-studied environment within the global ocean, with seawater found under sea ice particularly under-sampled. This project provides concentrations of select dissolved organic carbon compounds found in under-ice seawater sampled between March and May 2023. The dissolved org...

2026-07-02 | MTBLS12381 | MetaboLights
ProteomicsImproved data acquisition settings on Q Exactive HF-X Hybrid Quadrupole-Orbitrap and Orbitrap Fusion Lumos Tribrid mass spectrometers for proteomic analysis of limited samples
Deep proteomic profiling of complex biological and medical samples available at low nanogram and subnanogram levels is still challenging. To generate the most thorough and informative nanoflow liquid chromatography-tandem mass spectrometry-based proteomic profiling results for a limited sample analy...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-02-07 | MSV000091218 | MassIVE
ProteomicsQuantitative phosphoproteomics for nocodazole treated cells measured by Lumos DIA
Phosphoproteomic DIA-MS quantitative dataset for nocodazole treated cells (or “PhosDIA” in short). The MS samples injected in a previous publication for developing the IPF, an algorithm for identifying post-translationally modified peptides, were herein re-measured by a new, powerful Orbitrap Lumos ...
ORGANISM(S): Homo sapiens (Human) 
2020-06-08 | PXD017476 | Pride
Phosphoproteomics U2os cells Dia Nocodazle Lumos Cell cycle 
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