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TranscriptomicsAutonomous extracellular matrix remodeling controls a progressive adaptation in muscle stem cell regenerative capacity during development
Muscle stem cells (MuSC) exhibit distinct behaviors during successive phases of developmental myogenesis. However, how their transition to adulthood is regulated is poorly understood. Here we show that fetal MuSC resist progenitor specification and exhibit altered division dynamics, intrinsic featur...
ORGANISM(S): Mus musculus 
2016-01-20 | E-GEOD-76989 | biostudies-arrayexpress
TranscriptomicsAbnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient mice
Laminins are major constituents of basement membranes and are essential for tissue homeostasis. Laminin-511 is highly expressed in the intestine and its absence causes severe malformation of the intestine and embryonic lethality. To understand the mechanistic role of laminin-511 in tissue homeostasi...
ORGANISM(S): Mus musculus 
2012-06-29 | E-GEOD-31334 | biostudies-arrayexpress
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