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ProteomicsAn environmentally relevant mixture of organophosphate esters induces cholesterol biosynthesis in THP-1 macrophages
Organophosphate esters (OPEs), widely used as flame retardants and plasticizers, are environmental toxicants known to disrupt lipid metabolism. Although most studies have focused on individual OPEs, environmental exposures typically involve complex mixtures. Our previous studies demonstrated that a ...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD067007 | Pride
Macrophage Flame retardants Organophosphate esters Mixture Lipid droplets Cholesterol biosynthesis Proteomics 
TranscriptomicsImpact of Exposure to an Environmentally Relevant Mixture of Organophosphate Esters on the Adrenal Glands of Sprague Dawley Rats
To investigate the gene expression changes observed with exposure to organophosphate esters in the adrenal glands of Sprague Dawley rats.
ORGANISM(S): Rattus norvegicus 
2025-01-01 | GSE275797 | GEO
GenomicsImpact of Exposure to an Environmentally Relevant Mixture of Organophosphate Esters on the Adrenal Glands of Sprague Dawley Rats
Impact of Exposure to an Environmentally Relevant Mixture of Organophosphate Esters on the Adrenal Glands of Sprague Dawley Rats
PRJNA1153022 | ENA
UnknownImproved and Novel Methods for Investigating Organophosphate Esters in Particulate Matter.
Not available
S-EPMC12621544 | biostudies-literature
GenomicsToxicological Mechanisms and Potencies of Organophosphate Esters in KGN Human Ovarian Granulosa Cells as Revealed by High-throughput Transcriptomics
Toxicological Mechanisms and Potencies of Organophosphate Esters in KGN Human Ovarian Granulosa Cells as Revealed by High-throughput Transcriptomics
PRJNA1010940 | ENA
UnknownOrganophosphate esters in Tianshan glacier runoff: Occurrence, degradation, risk, and flux.
Not available
S-EPMC12744661 | biostudies-literature
GenomicsHouse Dust-Derived Mixtures of Organophosphate Esters Alter the Phenotype, Function, Transcriptome, and Lipidome of KGN Human Ovarian Granulosa Cells
House Dust-Derived Mixtures of Organophosphate Esters Alter the Phenotype, Function, Transcriptome, and Lipidome of KGN Human Ovarian Granulosa Cells
PRJNA1037087 | ENA
GenomicsImpacts of Gestational FireMaster 550 (FM 550) Exposure on the Neonatal Cortex are Sex Specific and Largely Attributable to the Organophosphate Esters
Impacts of Gestational FireMaster 550 (FM 550) Exposure on the Neonatal Cortex are Sex Specific and Largely Attributable to the Organophosphate Esters
PRJNA870309 | ENA
UnknownAssociations between exposure to organophosphate esters and overactive bladder in U.S. adults: a cross-sectional study.
Not available
S-EPMC10666646 | biostudies-literature
UnknownEmissions and fate of organophosphate esters in outdoor urban environments.
Not available
S-EPMC9977944 | biostudies-literature
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