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Mammalian orthoreoviruses (reoviruses) are nonenveloped, double-stranded RNA viruses that assemble progeny particles in cytoplasmic viral factories (VFs) and exit some types of cells using a nonlytic release mechanism. In human brain microvascular endothelial cells (HBMECs), progeny reovirus virions...
ORGANISM(S): Homo sapiens (Human) Orthoreovirus 
2025-10-10 | PXD068971 | Pride
Understanding the genomic toolkit that enabled animal terrestrialization, the shift from aquatic to terrestrial habitats, is key to uncovering the evolutionary origins of land biodiversity. Yet, the genomic basis of the physiological and metabolic adaptations required for life on land remains poorly...
ORGANISM(S): Obama nungara Schmidtea mediterranea (Freshwater planarian flatworm) 
2026-04-06 | PXD074775 | Pride
Animal terrestrialisation, the transition from aquatic to land environments, is one of the most impactful events in animal evolution, having occurred independently across several phyla. Yet, whether these transitions relied on a conserved genomic toolkit remains unexplored. To address this gap, we i...
ORGANISM(S): Obama nungara Siphonaria pectinata Leptonemertes chalicophora Schmidtea mediterranea (Freshwater planarian flatworm) Lineus sanguineus Litoditis marina Phorcus turbinatus Eisenia fetida Caenorhabditis elegans Theba pisana Porcellio scaber Ligia oceanica Physella Hirudo medicinalis Arenicola marina Ooperipatellus viridimaculatus 
2026-06-15 | PXD064337 | Pride
Mycosis fungoides patients who develop tumors or extracutaneous involvement usually have a poor prognosis with no curative therapy available so far. In the present EORTC multicenter study, the genomic profile of 41 skin biopsies from tumor-stage mycosis fungoides was analyzed using a high-resolution...
ORGANISM(S): Homo sapiens 
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