Actinoplanes sp. SE50/110 produces the diabetes type II drug acarbose only during the growth phase and not in the stationary phase. This correlation between the course of the cell growth and the biosynthesis could be due to a decreasing expression of the acarbose biosynthesis genes until the station...
ORGANISM(S): Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)