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A genetic association between the ANP32A gene and osteoarthritis has been suggested. We compared transcriptome profiles of the articular cartilage and subchondral bone from mice deficient in ANP32A with wild-type mice to get insights into the role of ANP32A in the pathogenesis of ostearthritis.
ORGANISM(S): Mus musculus 
2018-06-07 | GSE108036 | GEO
Comparative analysis of cartilage tissue from ANP32A knockout mice and wildtype C57/Bl6 mice
In osteoarthritis (OA), impairment of cartilage regeneration can be related to a defective chondrogenic differentiation of mesenchymal stromal cells (MSCs). Therefore, understanding the proteomic- and metabolomic-associated molecular events during the chondrogenesis of MSCs could provide alternative...
ORGANISM(S): Homo sapiens (Human) 
2020-01-27 | PXD012879 | Pride
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