Osteoblast - OmicsDI

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Repository

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Tissue

Osteoblast (24)
Cell culture (13)
Bone marrow (5)
Bone (4)
Mesenchymal stem cell of the bone marrow (3)
Bone matrix (2)
Dental pulp (2)
Mesenchymal cell (2)
Osteoblast differentiation (2)
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Blood (1)
B cell (1)
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Bone tissue (1)
Brain (1)
Breast (1)
Calvarial osteoblast (1)
Calvarium (1)
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Cranium (1)
Endothelial cell of umbilical vein (1)
Extracellular vesicle (1)
Fibroblast (1)
Gingival fibroblast (1)
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Disease

Normal (3)
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Disease free (3)
Glucocorticoid-remediable aldosteronism (2)
Osteoarthritis (2)
Osteonecrosis (2)
Shwachman-Diamond syndrome (1)
Sagittal craniosynostosis (1)
Metopic craniosynostosis (1)
Lambdoid craniosynostosis (1)
Coronal craniosynostosis (1)
Paget's disease of bone (1)
With bone lytic lesion (1)
Monoclonal gammopathy of unknown significance (MGUS) (1)
Osteocytes/osteoblasts (1)
Aortic valve stenosis (1)
Bone disease (1)
Bone giant cell tumor (1)
Bone osteosarcoma (1)
Burkitt lymphoma (1)
Cryptococcal meningitis (1)
Osteogenesis imperfecta (1)
Pancreatic cancer (1)
Prostate cancer (1)
Proteus syndrome (1)
Zika virus congenital syndrome (1)

Technology Type

Mass Spectrometry (49)
Shotgun proteomics (30)
Bottom-up proteomics (5)
Mass spectrometry assay (4)
Mass spectrometry (4)
Affinity purification coupled with mass spectrometry proteomics (4)
SWATH MS (4)
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Data-independent acquisition (2)
Top-down proteomics (2)
ESI (1)
HDMSE (1)

Instrument Platform

Illumina NovaSeq 6000 (6)
Liquid Chromatography MS - positive - reverse phase (5)
Liquid Chromatography MS - negative - reverse phase (5)
Orbitrap Fusion Lumos (4)
Illumina NovaSeq X (3)
Illumina HiSeq 2000 (3)
Illumina HiSeq 4000 (3)
NextSeq 500 (3)
Feature Extraction Version: 7.0,10.5 (2)
Agilent G2565AA and G2565BA Microarray Scanner (2)
ScanArray [PerkinElmer] (2)
Illumina Genome Analyzer II (2)
Illumina MiSeq (2)
Illumina HiSeq 2500 (2)
Orbitrap Fusion (2)
Liquid Chromatography MS - negative - hilic (2)
D1000 ScreenTape Analysis, Qubit Fluorometer. (1)
Scanner Genechip 3000 7G (1)
Mouse Drawer System (1)
FACS Aria II (1)
GenePix Professional 4200A [Axon Instruments] (1)
NA (1)
NextSeq 2000 (1)
Illumina HiSeq 1000 (1)
Illumina HiSeq 3000 (1)
LTQ Orbitrap (1)
Orbitrap Eclipse (1)
Orbitrap Exploris 480 (1)
Q-Exactive (1)
Xevo G2-S QTof (1)

Publication Date

2026 (92)
2014 (70)
2024 (69)
2012 (67)
2025 (66)
2023 (63)
2022 (61)
2021 (59)
2013 (54)
2016 (50)
2010 (47)
2015 (44)
2008 (34)
2019 (32)
2020 (30)
2018 (26)
2009 (24)
2011 (20)
2007 (19)
2017 (15)
2005 (9)
2004 (8)
2006 (4)
2002 (1)

CHEBI ID

CHEBI:75004 (2)
CHEBI:5417 (2)
CHEBI:75013 (2)
CHEBI:17992 (2)
CHEBI:17033 (2)
CHEBI:19702 (2)
CHEBI:32365 (2)
CHEBI:35704 (2)
CHEBI:4828 (2)
CHEBI:18132 (2)
CHEBI:36313 (2)
CHEBI:15753 (2)
CHEBI:16525 (2)
CHEBI:17802 (2)
CHEBI:15760 (2)
CHEBI:17311 (2)
CHEBI:17748 (2)
CHEBI:30832 (2)
CHEBI:28875 (2)
CHEBI:28842 (2)
CHEBI:19289 (2)
CHEBI:16196 (2)
CHEBI:27248 (2)
CHEBI:16335 (2)
CHEBI:40992 (2)
CHEBI:7916 (2)
CHEBI:73024 (2)
CHEBI:18019 (2)
CHEBI:15891 (2)
CHEBI:21547 (2)

Metabolite Name

N6,N6,N6-Trimethyl-L-lysine (3)
Taurine (3)
Creatine (3)
Citalopram aldehyde (2)
Delphinidin 3-sambubioside (2)
Behenic acid (2)
5-Methylthioribose (2)
D-Serine (2)
Cysteineglutathione disulfide (2)
N2,N2-Dimethylguanosine (2)
5-Aminopentanoic acid (2)
Thymine (2)
Sphingosine (2)
Niacinamide (2)
L-Lysine (2)
4-Pyridoxic acid (2)
Kynurenic acid (2)
Phytosphingosine (2)
Guanidinosuccinic acid (2)
L-Arginine (2)
Coumarin (2)
Acetylcarnitine (2)
L-Histidine (2)
Indole (2)
Choline (2)
Phenylacetylglycine (2)
Tauroursodeoxycholic acid (2)
Oleamide (2)
Tyramine (2)
Adenosine (2)

First Public Date

2026 (115)
2014 (113)
2024 (85)
2023 (70)
2025 (68)
2022 (61)
2021 (54)
2020 (28)
2019 (22)
2018 (22)
2016 (21)
2015 (17)
2017 (16)
2013 (8)

Modelling Approach

Ordinary differential equation model (5)

Lab affiliation

head of Laboratory of Regenerative Biomedicine, Institute of Cytology, Russian Academy of Sciences (2)
Assistant Professor of Medicine Department of Medicine Tulane University School of Medicine 1430 Tulane Avenue, New Orleans, LA,70114 (1)
Basic Research Lab for “Epigenetic Regeneration of Aged Skeleto-Muscular System (ERASMUS)”, Department of Molecular Genetics and Dental Pharmacology, School of Dentistry, Dental Research Institute, Seoul National University, Seoul, South Korea (1)
Bone and Cartilage Research Unit, Arthropôle Liège, University of Liège, Liège, Belgium (1)
Canadian Blood Services, Centre for Innovation, Ottawa, Ontario, Canada; Biochemistry, Microbiology and Immunology department, University of Ottawa, Ottawa, Canada. (1)
Centre for Oral, Clinical and Translational Science, King's College London, London, United Kingdom (1)
Chief, Section of Research and Tissue Engineering, Department of Plastic Surgery, University Medical Center Freiburg, Germany (1)
College of Life and Health Sciences, Northeastern University, Liaoning, Shenyang, China (1)
Cornell University (1)
Cyrus Tang Medical Institute, Soochow University (1)
DIVAS, University of Milan (1)
Department of Biochemistry and Molecular Biology, University of Southern Denmark (1)
Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro, 3810-193 Aveiro, Portugal. (1)
Department of Molecular Medicine (DMM), Biochemistry Unit, Center for Health Technologies (CHT), UdR INSTM University of Pavia, Pavia, Italy (1)
Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research – UFZ, Leipzig, Germany (1)
Department of Neurosciences, School of Medicine, Case Western Reserve University, 10900 Euclid Ave, Cleveland, Ohio, 44106 (1)
Department of Orthopaedic Surgery, University of Michigan School of Medicine, A. Alfred Taubman Biomedical Sciences Research Building, Room 2009, Ann Arbor, MI, 48109 (1)
Department of Orthopaedics and Traumatology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China (1)
Department of Surgery, Medicine, Dentistry and Morphological Sciences with Interest in Transplant,Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Italy. (1)
Departments of Surgery and Biomedical Sciences Cedars-Sinai Medical Center (1)
Erasmus MC, Rotterdam (1)
Fujian Medical University (1)
Head Proteomics Core Facility Medical University of Vienna Clinical Department of Laboratory Medicine (1)
Helmholtz Centre for Environmental Research - UFZ Department for Molecular Systems Biology (MOLSYB) Functional genomics group Leipzig/Germany (1)
Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany (1)
Institute Krems Bioanalytics, IMC University of Applied Sciences, 3500 Krems, Austria (1)
Institute of Medical Microbiology, Jena University Hospital, Jena, Germany (1)
Institute of Neuroimmunology of Slovak Academy of Sciences (1)
Institute of cytology of the Russian Academy of Science (1)
Instituto de Investigaciones Sanitarias de Santiago de Compostela (1)

IsPrivate

False (5)

Classification

bacteria (1)

Modification

4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (255)
RNA-seq of coding RNA (26)
ChIP-seq (18)
Unknown experiment type (6)
Comparative genomic hybridization by array (4)
Methylation profiling by array (4)
Transcription profiling by RT-PCR (3)
MicroRNA profiling by array (3)
Animal - High-throughput sequencing (2)
Capture-C (2)
RNA-seq of coding RNA from single cells (2)
Transcription profiling by SAGE (1)
MicroRNA profiling by high-throughput sequencing (1)
ChIP-chip by tiling array (1)
Human - High-throughput sequencing (1)
Human - One-color microarray (1)
Spatial transcriptomics by high-throughput sequencing (1)
ATAC-seq (1)
Other (1)
RNA-seq of total RNA (1)

Release Date

2022 (467)
2021 (405)
2023 (394)
2025 (359)
2020 (351)
2024 (291)
2019 (288)
2018 (264)
2016 (230)
2017 (222)
2015 (218)
2014 (209)
2012 (145)
2013 (138)
2010 (118)
2011 (105)
2008 (84)
2009 (79)
2026 (56)
2007 (37)
2006 (18)
2005 (17)
2004 (12)
2002 (7)
2003 (4)
2001 (2)
1999 (2)
2000 (1)
1998 (1)

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Untargeted LC-MS metabolomic comparison of canine osteosarcoma McKinley cells vs normal PEKCC2382 osteoblast cells

Untargeted LC-MS metabolomics analysis was performed on McKinley canine osteosarcoma cells (Group A) and PEKCC2382 normal canine osteoblast cells (Group B). This study screens characteristic differential metabolites and elucidates distinct metabolic phenotype discrepancies between malignant osteosar...

2026-07-28 | MTBLS14700 | MetaboLights

Transcription profiling of human hMADS cells during adipocyte and osteoblast differentiation

human adipocyte and osteoblast differentiation of hMADS cells

ORGANISM(S): Homo sapiens

2008-08-08 | E-MARS-10 | biostudies-arrayexpress

Sclerostin antibody increases trabecular bone and bone mechanical properties by increasing osteoblast activity damaged by whole-body irradiation in mice

Not available

ORGANISM(S): Mus musculus

ST001704 | MetabolomicsWorkbench

Characterization of distinct classes of differential gene expression in osteoblast cultures from non-syndromic craniosynostosis bone

We report on explant osteoblast cultures from human patients, demonstrating that there are at least three sub-types of non-syndromic craniosynostosis defined by similarity of gene expression profiles. Osteoblast growth in culture, 23 craniosynostosis skull samples (7 metopic; 8 coronal; 3 lambdoid; ...

ORGANISM(S): Homo sapiens

2014-07-16 | E-GEOD-55282 | biostudies-arrayexpress

Expression profiling of primary calvaria osteoblasts treated with miR-195 mimic, rhBMP2 and at different stages of differentiation

Primary calvaria osteoblasts from newborn mice were cultured. Cells were transfected with control and miR-195 mimic. Following serum starvation cells were treated with recombinant human BMP2 and expression was analyzed 4 hours after treatment. Additionally, osteoblast differentiation was induced wit...

ORGANISM(S): Mus musculus

2014-12-02 | E-MTAB-2450 | biostudies-arrayexpress

Transcription profiling of mouse C3H10T1/2 cells treated with Glis3 identifies its role in osteoblast differentiation and adipocyte differentiation

The expression of Glis3 in C3H10T1/2 cells promotes osteoblastic differentiation as indicated by the the induction of increase in alkaline phosphatase activity, an early marker of osteoblast differentiation, and increased expression of osteopontin, a late marker of osteogenesis. Glis3 acts synergist...

ORGANISM(S): Mus musculus

2008-06-13 | E-GEOD-5379 | biostudies-arrayexpress

Secretome Comparison of Mesenchymal Stromal Cells and Immature Osteoblasts

Osteoblasts are a key component of the endosteal hematopoietic stem cell (HSC) niche and have long been recognized with strong hematopoietic supporting activity. Osteoblast conditioned media (OCM) enhances the growth of hematopoietic progenitors in culture and modulate their engraftment activity. We...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2021-11-15 | MSV000088384 | MassIVE

Genomic Determinants of Gene Regulation by 1,25-Dihydroxyvitamin D3 During Osteoblast-Lineage Cell Differentiation [gene expression]

The biological effects of 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) on osteoblast differentiation and function differ significantly depending upon the cellular state of maturation. To explore this phenomenon mechanistically, we examined the impact of 1,25(OH)2D3 on the transcriptomes of both pre-oste...

ORGANISM(S): Mus musculus

2014-06-02 | E-GEOD-51514 | biostudies-arrayexpress

TGF-beta responsive gene in primary osteoblast.

Gene expression profiling of a total of 3,774 genes in primary osteoblastic cells treated with TGF-beta1 Keywords: cytokine response Primary osteoblasts cultured under serum-starved condition were treated or untreated with TGF-beta1 for 24 hr.

ORGANISM(S): Mus musculus

2009-04-28 | E-GEOD-11702 | biostudies-arrayexpress

Proteomic evaluation of human osteoblast responses to titanium implants over time

Titanium is widely used in bone prostheses due to its excellent biocompatibility and osseointegration capacity. To understand the effect of sandblasted acid-etched (SAE) Ti implants on the biological responses of human osteoblast (HOb), their proteomic profiles were analysed using nLC-MS/MS. The cel...

ORGANISM(S): Homo sapiens (Human)

2023-03-11 | PXD035986 | Pride

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