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ProteomicsThe OTUD6B-LIN28B-MYC axis determines cell cycle progression in multiple myeloma
Deubiquitylases (DUBs) remove ubiquitin from proteins. In the context of cancer, their inhibition can induce the degradation of oncoproteins, that may otherwise be “undruggable”. Multiple myeloma (MM) is the second most common hematological malignancy with poor outcome and high sensitivity towards u...
ORGANISM(S): Homo sapiens (Human) 
2022-10-12 | PXD027480 | Pride
Bioid Human Flag-ip Orbitrap Otud6b 
GenomicsRNA sequencing analysis of OTUD6B-knockdown KYSE30 cells
RNA sequencing analysis of OTUD6B-knockdown KYSE30 cells
PRJNA861139 | ENA
TranscriptomicsRNA sequencing analysis of OTUD6B-knockdown KYSE30 cells
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are using RNA sequencing analysis to test the effects of OTUD6B-knockdown on the mRNA of KYSE30 cells. Methods: KYSE30 cells were transfected with negative control or siO...
ORGANISM(S): Homo sapiens 
2023-04-01 | GSE209521 | GEO
UnknownDeubiquitinase OTUD6B Isoforms Are Important Regulators of Growth and Proliferation.
Not available
S-EPMC5290186 | biostudies-literature
UnknownOTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival.
Not available
S-EPMC11850729 | biostudies-literature
UnknownOTUD6B-AS1 Might Be a Novel Regulator of Apoptosis in Systemic Sclerosis.
Not available
S-EPMC6533854 | biostudies-literature
Genomics
RNA-Seq analysis of OTUD6B
PRJNA555489 | ENA
UnknownThe OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma.
Not available
S-EPMC9574752 | biostudies-literature
UnknownOtud6b induces pulmonary arterial hypertension by mediating the Calpain-1/HIF-1α signaling pathway.
Not available
S-EPMC11335297 | biostudies-literature
UnknownIdentification of OTUD6B as a new biomarker for prognosis and immunotherapy by pan-cancer analysis.
Not available
S-EPMC9425067 | biostudies-literature
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