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Transplantation is currently the best treatment option for end-stage renal disease (ESRD) patients. However, acute rejection (AR) is the main source of failure in renal transplantation. The current gold standard for diagnosis of AR involves renal biopsy, but it is invasive, time consuming, costly an...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD015336 | Pride
Background: Autosomal dominant osteopetrosis type II (ADO2) is a rare human genetic disease that has been broadly studied as an important osteopetrosis model; however, there are no disease-specific induced pluripotent stem cells (ADO2-iPSCs) that may be valuable for understanding the pathogenesis an...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD014227 | Pride
Background Systemic lupus erythematosus (SLE) is a severe systemic autoimmune disease with multiple manifestations. Lysine crotonylation (Kcr) is a newly discovered post-translational modification (PTM) epigenetic pattern which may affect gene expression and linked to diseases causally. Methods We ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD042217 | Pride
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