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MetabolomicsLipidOA: A Machine-Learning and Prior-Knowledge-Based Tool for Structural Annotation of Glycerophospholipids
The Paternò-Büchi (PB) reaction is a carbon-carbon double bond (C═C)-specific derivatization reaction that can be used to pinpoint the location(s) of C═C(s) in unsaturated lipids and quantitate the location of isomers when coupled with tandem mass spectrometry (MS/MS). As the data of PB-MS/MS are in...
2022-11-23 | MTBLS6075 | MetaboLights
ModelsOuyang2014 - photomorphogenic UV-B signalling network
Ouyang2014 - photomorphogenic UV-B signalling network This model is described in the article: Coordinated photomorphogenic UV-B signaling network captured by mathematical modeling. Ouyang X, Huang X, Jin X, Chen Z, Yang P, Ge H, Li S, Deng XW. Proc. Natl. Acad. Sci. U.S.A. 201...
2024-09-02 | BIOMD0000000545 | BioModels
TranscriptomicsExpression data from a new FACS approach isolated hESC derived endoderm cells using transcription factors
We show that high quality microarray gene expression profiles can be obtained following FACS sorting of cells using combinations of transcription factors. We use this transcription factor FACS (tfFACS) methodology to perform a genomic analysis of hESC-derived endodermal lineages marked by combinatio...
ORGANISM(S): Homo sapiens 
2011-08-23 | E-GEOD-24135 | biostudies-arrayexpress
GenomicsGenome Wide Mapping of Foxo1 Binding-sites in Murine T Lymphocytes
The Forkhead box O (Foxo) family of transcription factors has a critical role in controlling the development, differentiation, and function of T cells. However, the direct target genes of Foxo transcription factors in T cells have not been well characterized. In this study, we focused on mapping the...
ORGANISM(S): Mus musculus 
2014-08-19 | E-GEOD-60470 | biostudies-arrayexpress
TranscriptomicsComparison between Borrelia burgdorferi wild type strain and cognate rpoS, rpoN and rrp2 mutants
The RpoN-RpoS alternative sigma factor pathway is essential for key adaptive responses by Borrelia burgdorferi, particularly those involved in the infection of a mammalian host. A putative response regulator, Rrp2, ostensibly is required for activation of the RpoN-dependent transcription of rpoS. ...
ORGANISM(S): Borrelia burgdorferi 
2008-09-09 | E-GEOD-11284 | biostudies-arrayexpress
UnknownSingle-cell structural lipidomics using a miniature dual-LIT mass spectrometer.
Not available
S-EPMC12766753 | biostudies-literature
TranscriptomicsTranscriptional profiling of the Borrelia burgdorferi bb0647 mutant
RNA was isolated from late-log pahse wild-type Borrelia burgdorferi B31 and the bb0647 mutant grown in BSKH media at 37 degree, 5% CO2. cDNA was synthesized, labeled and hybridized to the 70mer oligonucleotide B. burgdorferi array. Slides were scanned using axon scanner and image were analyzed using...
ORGANISM(S): Borrelia burgdorferi 
2010-05-15 | E-GEOD-17422 | biostudies-arrayexpress
UnknownFast protein analysis enabled by high-temperature hydrolysis.
Not available
S-EPMC8162451 | biostudies-literature
UnknownGenome-wide CRISPR knockout screens identify NCAPG as an essential oncogene for hepatocellular carcinoma tumor growth.
Not available
S-EPMC6662966 | biostudies-literature
Transcriptomics3-anhydro-6-hydroxy-ophiobolin A inhibits the replication of influenza A virus in vitro and in vivo
Influenza is a major cause of morbidity and mortality worldwide, and the emerging drug resistance poses an increasing challenge to the treatment of influenza virus infection. Therefore, the development of a novel antiviral drugs has become an urgent task to combat against the influenza viruses that ...
ORGANISM(S): Homo sapiens 
2015-11-05 | E-GEOD-58741 | biostudies-arrayexpress
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