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N6-methyladenosine (m6A) is the most prevalent mRNA modification with diverse regulatory roles in mammalian cells. While its functions are well-documented in mouse embryonic stem cells (mESCs), its role in human pluripotent stem cells (hPSCs) remains to be fully explored. METTL3 is the main enzyme r...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD056046 | Pride
Drug repurposing offers a cost-effective strategy for accelerating therapeutic development. This study identifies trazodone, an FDA-approved anti-depressant, as a promising therapeutic candidate for Alzheimer’s disease (AD). We show that trazodone use in patients with AD is associated with decreased...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-02 | PXD071776 | Pride
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