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TranscriptomicsGene expression in bovine ovarian follicle theca interna
Thecal tissue forms a layer around the follicle just prior to antral stage and grows with the follicle (containing an oocyte) as it matures. The innermost component (theca interna) supplies hormones and other factors necessary to the growth and development of the granulosa and oocyte. Most follicles...
ORGANISM(S): Bos taurus 
2014-05-20 | E-GEOD-49505 | biostudies-arrayexpress
MetabolomicsBCAA insufficiency leads to premature ovarian insufficiency via ceramide-induced elevation of ROS (targeted metabolomics)

Premature ovarian insufficiency (POI) is a disease featured by early menopause before 40 years of age, accompanied by an elevation of follicle-stimulating hormone. Though POI affects many aspects of women's health, its major causes remain unknown. Many clinical studies have shown that POI patient...

2024-09-26 | MTBLS6267 | MetaboLights
MetabolomicsBCAA insufficiency leads to premature ovarian insufficiency via ceramide-induced elevation of ROS (untargeted lipidomics)

Premature ovarian insufficiency (POI) is a disease featured by early menopause before 40 years of age, accompanied by an elevation of follicle-stimulating hormone. Though POI affects many aspects of women's health, its major causes remain unknown. Many clinical studies have shown that POI patient...

2024-09-26 | MTBLS6249 | MetaboLights
TranscriptomicsThe transitional Gene Expression Profiling of Ovarian Follicle Treated with Indomethacin and RU486 in Rats
Indomethacin (an inhibitor of prostaglandin synthesis) and RU486 (mifepristone, progesterone receptor antagonist) are well known compounds which impair follicle rupture in rats, nevertheless the histopahotlogical figures of these follicle were different in detail due to the difference of the pathway...
ORGANISM(S): Rattus norvegicus 
2014-02-01 | E-GEOD-54584 | biostudies-arrayexpress
TranscriptomicsGene expression in bovine ovarian follicle granulosa
Granulosa cells mature and die as ovarian follicles enlarge and die (undergo atresia) under the influence of hormones and intrafollicular factors. Later in follicular development, a fluid-filled antrum is formed, a process which is accompanied by a high rate of atresia. These small antral follicles ...
ORGANISM(S): Bos taurus 
2014-05-20 | E-GEOD-39589 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Bos taurus granulosa and theca cells during ovarian antral follicle development.
Coordinated interactions between ovarian granulosa and theca cells are required for female endocrine function and fertility. To elucidate these interactions the regulation of the granulosa and theca cell transcriptomes during bovine antral follicle development were investigated. Granulosa cells and ...
ORGANISM(S): Bos taurus 
2008-11-04 | E-GEOD-11495 | biostudies-arrayexpress
TranscriptomicsInhibitory Actions of Anti-MM-CM-
The current study was designed to investigate the actions of Anti-MM-CM-
ORGANISM(S): Rattus norvegicus 
2011-03-04 | E-GEOD-25629 | biostudies-arrayexpress
MetabolomicsUHPLC-OE-MS metabolic profile of follicular fluid in patients with ovarian endometriosis: a pilot study of an endometriosis cohort

BACKGROUND: Endometriosis is a common benign gynaecological disorder. A number of studies have confirmed that the occurrence of disease in endometriosis patients is associated with metabolic changes in biological fluids and tissues. We set out to investigate the metabolic charact...

2024-02-20 | MTBLS8621 | MetaboLights
TranscriptomicsExpression profile of 16C ovarian follicle cells
We use DSN normalized RNA-seq to transcriptionally profile FACS sorted 16C ovarian follicle cells. These data provide insights into the developmental control of gene expression programmed gene amplificaton. Follicle cells were isolated from whole ovaries by trypsinization and filtering and stained w...
ORGANISM(S): Drosophila melanogaster 
2011-05-27 | E-GEOD-29526 | biostudies-arrayexpress
TranscriptomicsNeurotrophin NT3 promotes ovarian primordial to primary follicle transition
Neurotrophins are growth factors that are known to have a role in promoting cell survival and differentiation. The focus of the current study is to examine the role of neurotrophins in regulating ovarian primordial follicle development. Ovaries from 4-day old rats were placed into organ culture and ...
ORGANISM(S): Rattus norvegicus 
2010-02-21 | E-GEOD-20358 | biostudies-arrayexpress
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